HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: RPRD2 (Q5VT52)
Regulation of nuclear pre-mRNA domain-containing protein 2
Gene: RPRD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.535

Property	Details
Experiments	30344098, 23080069
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 1461
+	Hs
		905964 PP1A_HUMAN (1-323): 0: 579: 90.66		RPRD2_HUMAN (27-1461): 3.96e-149: 494: 100.00
+	Hs
		738062 PP1G_HUMAN (1-323): 0: 603: 100.00		RPR1B_HUMAN (20-332): 1.38e-61: 216: 24.14
+	Hs
		577593 PP1G_HUMAN (1-323): 0: 603: 100.00		SON_HUMAN (145-1398): 1.82e-27: 124: 11.90
+	Dm
		54320 Q8T0U6_DROME (19-323): 0: 535: 83.39		A1Z9J3_DROME (130-1336): 4.3e-41: 169: 12.14
+	Hs
		738038 PP1G_HUMAN (1-323): 0: 603: 100.00		TARA_HUMAN (409-1461): 1.53e-16: 88.3: 9.87
+	Hs
		906127 PP1A_HUMAN (1-323): 0: 579: 90.66		TARA_HUMAN (409-1461): 1.53e-16: 88.3: 9.87
+	Hs
		915248 PP2AB_HUMAN (8-312): 2.02e-178: 497: 46.73		CTTB2_HUMAN (165-743): 2.24e-40: 166: 14.00
+	Hs
		930938 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		CTTB2_HUMAN (165-743): 2.24e-40: 166: 14.00
+	Hs
		905894 PP1A_HUMAN (1-323): 0: 579: 90.66		MDC1_HUMAN (193-1458): 7.63e-14: 79.4: 9.95
+	Dm
		113980 PP1B_DROME (1-323): 0: 552: 82.48		M9PB30_DROME (148-859): 3.59e-20: 100: 9.43
+	Hs
		906595 PP1B_HUMAN (1-322): 0: 560: 86.89		TARA_HUMAN (409-1461): 1.53e-16: 88.3: 9.87
+	Hs
		930846 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		MDC1_HUMAN (193-1458): 7.63e-14: 79.4: 9.95