HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: SH24A (Q9H788)
SH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38)
Gene: SH2D4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 454
+	Hs
		906136 PP1A_HUMAN (1-323): 0: 579: 90.66		SH24A_HUMAN (1-454): 1.2e-138: 407: 100.00
+	Hs
		906600 PP1B_HUMAN (1-322): 0: 560: 86.89		SH24A_HUMAN (1-454): 1.2e-138: 407: 100.00
+	Hs
		737723 PP1G_HUMAN (1-323): 0: 603: 100.00		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		905820 PP1A_HUMAN (1-323): 0: 579: 90.66		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Hs
		111444 PP1B_HUMAN (1-322): 0: 560: 86.89		J3QRU1_HUMAN (200-454): 4.85e-42: 158: 15.39
+	Hs
		433310 PP1B_HUMAN (1-322): 0: 560: 86.89		YES_HUMAN (201-454): 1.68e-41: 156: 15.44
+	Hs
		906402 PP1B_HUMAN (1-322): 0: 560: 86.89		GRB2_HUMAN (310-454): 1.67e-42: 151: 24.83
+	Mm
		906650 PP1B_MOUSE (1-322): 0: 560: 86.89		GRB2_MOUSE (310-454): 9.77e-43: 151: 24.83
+	Hs
		796535 PP1A_HUMAN (1-323): 0: 579: 90.66		KSYK_HUMAN (273-440): 2.84e-14: 76.8: 23.08
+	Hs
		522884 PP2AB_HUMAN (8-312): 2.02e-178: 497: 46.73		SRC_HUMAN (238-454): 4.15e-42: 158: 14.56
+	Hs
		796542 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		KSYK_HUMAN (273-440): 2.84e-14: 76.8: 23.08