Protein: SYSC
Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser) synthetase)

Gene: SYSC, SES1
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: P07284

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002181 - cytoplasmic translation
GO:0004828 - serine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

426458

PEX21
Peroxisomal protein PEX21

4

0

Small-scale

0.667

High

426456

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

2

High-throughput

0.584

High

426422

RAD53
Serine/threonine-protein kinase RAD53

2

0

High-throughput

0.569

High

426479

HRP1
Nuclear polyadenylated RNA-binding protein 4

2

0

High-throughput

0.563

High

426451

RV167
Reduced viability upon starvation protein 167

1

1

High-throughput

0.536

High

426462

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

426478

DUF1
DUB-associated factor 1

1

2

High-throughput

0.536

High

416267

SIR3
Regulatory protein SIR3

1

0

High-throughput

0.513

High

425262

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

426431

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

426446

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.513

High

426421

MCK1
Protein kinase MCK1

1

2

High-throughput

0.501

High

426424

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

426426

KCC4
Probable serine/threonine-protein kinase KCC4

1

4

High-throughput

0.501

High

426429

PRR1
Serine/threonine-protein kinase PRR1

1

1

High-throughput

0.501

High

426434

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

3

High-throughput

0.501

High

426441

HSL1
Probable serine/threonine-protein kinase HSL1

1

4

High-throughput

0.501

High

426442

NNK1
Nitrogen network kinase 1

1

2

High-throughput

0.501

High

426457

IKS1
Probable serine/threonine-protein kinase IKS1

1

2

High-throughput

0.501

High

426463

KIN4
Serine/threonine-protein kinase KIN4

1

4

High-throughput

0.501

High

426464

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

3

High-throughput

0.501

High

426465

STE20
Serine/threonine-protein kinase STE20

1

1

High-throughput

0.501

High

426470

HRK1
Serine/threonine-protein kinase HRK1

1

3

High-throughput

0.501

High

426443

DRE2
Fe-S cluster assembly protein DRE2

1

0

High-throughput

0.493

High

426474

CSN10
COP9 signalosome complex subunit 10

1

0

High-throughput

0.493

High

426468

SEN15
tRNA-splicing endonuclease subunit SEN15

1

1

High-throughput

0.489

High

426476

AIR2
Protein AIR2

1

1

High-throughput

0.489

High

409588

KAPC
cAMP-dependent protein kinase type 3

1

0

High-throughput

0.480

High

426427

SSK22
Serine/threonine-protein kinase SSK22

1

0

High-throughput

0.480

High

342820

ENO2
Enolase 2

1

1

High-throughput

0.479

High

365589

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.479

High

406661

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

426419

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

426425

SIS1
Protein SIS1

1

4

High-throughput

0.479

High

426428

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

426432

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

426433

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

426436

HOG1
Mitogen-activated protein kinase HOG1

1

2

High-throughput

0.479

High

426438

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

426439

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

426447

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

426448

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

426449

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

426450

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

426452

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

426455

OTU1
Ubiquitin thioesterase OTU1

1

1

High-throughput

0.479

High

426459

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

426460

HST2
NAD-dependent protein deacetylase HST2

1

2

High-throughput

0.479

High

426466

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

426475

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

426423

SAN1
Protein SAN1

1

0

Small-scale

0.460

High

426435

CDC3
Cell division control protein 3

1

0

High-throughput

0.460

High

340583

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

389194

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

410857

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

426420

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.458

High

426444

ADH5
Alcohol dehydrogenase 5

1

0

High-throughput

0.458

High

426461

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

426467

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

426472

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

426477

HAA1
Transcriptional activator HAA1

1

0

High-throughput

0.458

High

426418

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

426437

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

426453

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

426440

CASP
Protein CASP

1

3

High-throughput

0.439

High

426430

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

426445

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

426469

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

426471

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

426473

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.437

High

426454

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024