HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PIHD1 (Q9NWS0)
PIH1 domain-containing protein 1 (Nucleolar protein 17 homolog)
Gene: PIH1D1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.732

Property	Details
Experiments	26186194, 28514442, 33961781, 26496610, 30344098, 24366813
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0019901 - protein kinase binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 290
+	Hs
		906164 PP1A_HUMAN (1-323): 0: 579: 90.66		PIHD1_HUMAN (1-290): 4.3e-126: 362: 100.00
+	Hs
		906613 PP1B_HUMAN (1-322): 0: 560: 86.89		PIHD1_HUMAN (1-290): 4.3e-126: 362: 100.00
+	Hs
		931021 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		PIHD1_HUMAN (1-290): 4.3e-126: 362: 100.00
+	Dm
		819207 PP11_DROME (5-323): 0: 569: 88.92		KTU_DROME (10-286): 3.41e-73: 242: 18.89
+	Dm
		819312 PP1B_DROME (1-323): 0: 552: 82.48		Q9VK57_DROME (37-287): 1.69e-80: 248: 27.15
+	Dm
		819252 PP1B_DROME (1-323): 0: 552: 82.48		KTU_DROME (10-286): 3.41e-73: 242: 18.89
+	Dm
		524612 PP12_DROME (5-303): 0: 551: 93.31		KTU_DROME (10-286): 3.41e-73: 242: 18.89
+	Dm
		984173 PP13_DROME (5-303): 0: 547: 91.64		KTU_DROME (10-286): 3.41e-73: 242: 18.89
+	Dm
		1249914 Q8T0U6_DROME (19-323): 0: 535: 83.39		Q9VK57_DROME (37-287): 1.69e-80: 248: 27.15