Interactor 1: RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (Nuclear integrity protein 1)
Gene: RPN12

Interactor 2: RPN3 (P40016)
26S proteasome regulatory subunit RPN3
Gene: RPN3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 11742986, 11805826, 37968396, 10675611, 16554755, 16429126, 31848235, 22195964
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, cross-linking study, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN8_PSD8_EIF3K~PCI, CSN8_PSD8_EIF3K~Rpn3_C
Common GO terms GO:0000502 - proteasome complex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 274
Sc

1 523
+ Hs
+ Dm
+ Dm

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Last updated: 11Aug2025