HitPredict

Interactor 1: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A

Interactor 2: PE2R3 (P43115)
Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)
Gene: PTGER3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	7tm_1~Pkinase
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 532 Hs			1 390
+	Hs
		600869 BMR1A_HUMAN (1-532): 5.05e-164: 477: 100.00		TA2R_HUMAN (43-380): 6.15e-65: 212: 33.73
+	Hs
		723275 BMR1A_HUMAN (1-532): 5.05e-164: 477: 100.00		APJ_HUMAN (37-390): 1.01e-63: 210: 14.41
+	Hs
		646023 AVR2A_HUMAN (81-530): 3.08e-111: 341: 32.56		PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00
+	Hs
		793098 AVR2B_HUMAN (81-529): 7.14e-111: 341: 30.02		PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00