HitPredict

Interactor 1: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0001525 - angiogenesis GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 532 Hs			1 196
+	Hs
		738322 BMR1A_HUMAN (1-532): 5.05e-164: 477: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		436181 BMR1A_HUMAN (1-532): 5.05e-164: 477: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		738320 BMR1A_HUMAN (1-532): 5.05e-164: 477: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		738321 BMR1A_HUMAN (1-532): 5.05e-164: 477: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		738521 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		738517 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		738519 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		436183 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		738527 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		738515 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		738516 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Mm
		983316 ACVL1_MOUSE (57-531): 1.67e-131: 393: 45.09		RAC2_MOUSE (1-196): 6.65e-76: 227: 53.57
+	Hs
		564434 TGFR1_HUMAN (26-532): 9.84e-139: 412: 49.22		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		738438 ACV1B_HUMAN (47-532): 1.83e-128: 385: 49.19		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		436182 ACV1B_HUMAN (47-532): 1.83e-128: 385: 49.19		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Mm
		983317 TGFR2_MOUSE (35-528): 7.09e-120: 366: 28.63		RAC2_MOUSE (1-196): 6.65e-76: 227: 53.57
+	Hs
		545365 BMPR2_HUMAN (49-525): 7.83e-113: 360: 28.04		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436293 BMPR2_HUMAN (49-525): 7.83e-113: 360: 28.04		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		564520 BMPR2_HUMAN (49-525): 7.83e-113: 360: 28.04		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120428 BMPR2_HUMAN (49-525): 7.83e-113: 360: 28.04		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98