HitPredict

Interactor 1: RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (Nuclear integrity protein 1)
Gene: RPN12

Interactor 2: RPN9 (Q04062)
26S proteasome regulatory subunit RPN9 (Proteasome non-ATPase subunit 7)
Gene: RPN9

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 11805826, 16554755, 16429126, 19217412, 37968396, 31848235, 22195964
Identification Methods tandem affinity purification, affinity chromatography technology, cross-linking study, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN8_PSD8_EIF3K~PCI, CSN8_PSD8_EIF3K~Rpn9_C
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0034515 - proteasome storage granule
and 1 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 274
Sc

1 393
+ Hs
+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025