Interactor 1: ACV1B (P36896)
Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)
Gene: ACVR1B
Interactor 2: TGFR2 (P37173)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: TGFBR2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.62 | 1.00 | 0.789 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Activin_recp~ecTbetaR2, PK_Tyr_Ser-Thr~Pkinase, PK_Tyr_Ser-Thr~TGF_beta_GS |
Common GO terms | GO:0001701 - in utero embryonic development GO:0004675 - transmembrane receptor protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane and 6 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
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Last updated: 15 Jul 2024