Protein: EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

Gene: EIFCL, EIF3CL
Organism: Homo sapiens
Interactions: 91
UniProt ID: B5ME19

Gene Ontology (top 5):
GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005852 - eukaryotic translation initiation factor 3 complex
GO:0006413 - translational initiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

81657

EIF3F
Eukaryotic translation initiation factor 3 subunit F

5

6

Small-scale

0.919

High

81719

EIF3M
Eukaryotic translation initiation factor 3 subunit M

4

3

High-throughput

0.903

High

81693

EIF3E
Eukaryotic translation initiation factor 3 subunit E

4

4

High-throughput

0.895

High

81743

EIF3L
Eukaryotic translation initiation factor 3 subunit L

3

2

High-throughput

0.861

High

81705

EIF3A
Eukaryotic translation initiation factor 3 subunit A

2

5

High-throughput

0.754

High

81660

EIF3H
Eukaryotic translation initiation factor 3 subunit H

5

7

High-throughput

0.716

High

81701

EIF3I
Eukaryotic translation initiation factor 3 subunit I

4

3

High-throughput

0.699

High

81659

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

2

High-throughput

0.691

High

81731

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.691

High

81689

TERA
Transitional endoplasmic reticulum ATPase

2

2

High-throughput

0.571

High

81664

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

4

High-throughput

0.536

High

81672

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

1

High-throughput

0.536

High

81678

HMGB2
High mobility group protein B2

1

2

High-throughput

0.536

High

81681

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.536

High

81682

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

4

High-throughput

0.536

High

81687

MAP2
Methionine aminopeptidase 2

1

1

High-throughput

0.536

High

81688

IF5
Eukaryotic translation initiation factor 5

1

3

High-throughput

0.536

High

81690

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

7

High-throughput

0.536

High

81706

CAPR1
Caprin-1

1

1

High-throughput

0.536

High

81704

CUL3
Cullin-3

2

1

High-throughput

0.533

High

81675

RAB5A
Ras-related protein Rab-5A

2

1

High-throughput

0.521

High

81673

H15
Histone H1.5

1

0

High-throughput

0.493

High

81663

ATG13
Autophagy-related protein 13

1

1

High-throughput

0.489

High

81680

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.489

High

81698

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

1

High-throughput

0.489

High

81708

CND2
Condensin complex subunit 2

1

1

High-throughput

0.489

High

81724

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.489

High

81735

ENY2
Transcription and mRNA export factor ENY2

1

1

High-throughput

0.489

High

81744

EMC9
ER membrane protein complex subunit 9

1

1

High-throughput

0.489

High

81671

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.479

High

81676

CD11B
Cyclin-dependent kinase 11B

1

6

High-throughput

0.479

High

81677

DDX6
Probable ATP-dependent RNA helicase DDX6

1

2

High-throughput

0.479

High

81697

RED1
Double-stranded RNA-specific editase 1

1

2

High-throughput

0.479

High

81699

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

81702

TCOF
Treacle protein

1

3

High-throughput

0.479

High

81709

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

1

High-throughput

0.479

High

81655

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

81658

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.437

High

81662

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.437

High

81667

ICAM1
Intercellular adhesion molecule 1

1

2

High-throughput

0.437

High

81668

RHOC
Rho-related GTP-binding protein RhoC

1

1

High-throughput

0.437

High

81669

CLCA
Clathrin light chain A

1

1

High-throughput

0.437

High

81670

CLCB
Clathrin light chain B

1

1

High-throughput

0.437

High

81674

CSK22
Casein kinase II subunit alpha'

1

8

High-throughput

0.437

High

81683

MAP1B
Microtubule-associated protein 1B

1

3

High-throughput

0.437

High

81686

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.437

High

81691

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.437

High

81692

CD81
CD81 antigen

1

1

High-throughput

0.437

High

81694

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.437

High

81695

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.437

High

81696

CSK21
Casein kinase II subunit alpha

1

9

High-throughput

0.437

High

81710

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.437

High

81712

BRD3
Bromodomain-containing protein 3

1

3

High-throughput

0.437

High

81713

KS6A2
Ribosomal protein S6 kinase alpha-2

1

7

High-throughput

0.437

High

81718

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

81725

CSK23
Casein kinase II subunit alpha 3

1

8

High-throughput

0.437

High

81727

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

81728

IGSF8
Immunoglobulin superfamily member 8

1

1

High-throughput

0.437

High

81730

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.437

High

81734

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

1

High-throughput

0.437

High

81738

HDAC6
Protein deacetylase HDAC6

1

1

High-throughput

0.437

High

81740

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.437

High

81741

TRI33
E3 ubiquitin-protein ligase TRIM33

1

2

High-throughput

0.437

High

81742

CD11A
Cyclin-dependent kinase 11A

1

6

High-throughput

0.437

High

81666

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.407

High

81700

STK4
Serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

81736

ANLN
Anillin

2

0

High-throughput

0.305

High

81685

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.279

Low

81665

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

81679

TKT
Transketolase

1

0

High-throughput

0.249

Low

81684

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

81703

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

81711

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

81720

SHLD2
Shieldin complex subunit 2

1

0

Small-scale

0.249

Low

81721

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

81722

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.249

Low

81726

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low

81729

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

81732

ECT2
Protein ECT2

1

0

High-throughput

0.249

Low

81739

DP13A
DCC-interacting protein 13-alpha

1

0

High-throughput

0.249

Low

81737

PICK1
PRKCA-binding protein

1

0

High-throughput

0.238

Low

81654

OSCRI
SCRIB overlapping open reading frame protein

1

0

High-throughput

0.232

Low

81656

SO1B7
Putative solute carrier organic anion transporter family member 1B7

1

0

High-throughput

0.232

Low

81661

CTR4
Cationic amino acid transporter 4

1

0

High-throughput

0.232

Low

81707

S29A2
Equilibrative nucleoside transporter 2

1

0

High-throughput

0.232

Low

81714

LETM2
LETM1 domain-containing protein LETM2, mitochondrial

1

0

High-throughput

0.232

Low

81715

S45A4
Solute carrier family 45 member 4

1

0

High-throughput

0.232

Low

81716

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.232

Low

81717

MFSD6
Major facilitator superfamily domain-containing protein 6

1

0

High-throughput

0.232

Low

81723

CTL5
Choline transporter-like protein 5

1

0

High-throughput

0.232

Low

81733

GHC1
Mitochondrial glutamate carrier 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025