HitPredict

Interactor 1: TGFR1 (P36897)
TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)
Gene: TGFBR1

Interactor 2: PEG10 (Q86TG7)
Retrotransposon-derived protein PEG10 (Embryonal carcinoma differentiation-regulated protein) (Mammalian retrotransposon-derived protein 2) (Myelin expression factor 3-like protein 1) (MEF3-like protein 1) (Paternally expressed gene 10 protein) (Retrotransposon gag domain-containing protein 3) (Retrotransposon-derived gag-like polyprotein) (Ty3/Gypsy-like protein)
Gene: PEG10

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15611116
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006915 - apoptotic process GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 503 Hs			1 708
+	Hs
		981125 ACVR1_HUMAN (10-500): 8.17e-136: 403: 49.30		PEG10_HUMAN (1-708): 0: 1000: 100.00
+	Hs
		122294 BMR1B_HUMAN (22-503): 1.21e-134: 400: 51.53		PEG10_HUMAN (1-708): 0: 1000: 100.00
+	Hs
		738368 BMR1A_HUMAN (21-503): 4.05e-134: 400: 50.92		PEG10_HUMAN (1-708): 0: 1000: 100.00
+	Hs
		738465 ACV1B_HUMAN (2-503): 6.8e-133: 396: 67.78		PEG10_HUMAN (1-708): 0: 1000: 100.00
+	Hs
		739532 ACVL1_HUMAN (6-498): 2.71e-130: 389: 47.21		PEG10_HUMAN (1-708): 0: 1000: 100.00
+	Hs
		740005 TGFR2_HUMAN (38-497): 1.43e-118: 361: 31.94		PEG10_HUMAN (1-708): 0: 1000: 100.00
+	Hs
		646045 AVR2A_HUMAN (53-497): 1.95e-107: 331: 30.20		PEG10_HUMAN (1-708): 0: 1000: 100.00
+	Hs
		1044921 AVR2B_HUMAN (53-498): 2.08e-105: 325: 30.50		PEG10_HUMAN (1-708): 0: 1000: 100.00