Protein: NU159
Nucleoporin NUP159 (Nuclear pore protein NUP159)

Gene: NU159, NUP159
Organism: Saccharomyces cerevisiae S288C
Interactions: 85
UniProt ID: P40477

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0000056 - ribosomal small subunit export from nucleus
GO:0000774 - adenyl-nucleotide exchange factor activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

632803

DBP5
ATP-dependent RNA helicase DBP5

5

12

Small-scale

0.932

High

823476

NUP82
Nucleoporin NUP82

17

4

Small-scale

0.764

High

577311

NSP1
Nucleoporin NSP1

13

19

Small-scale

0.759

High

825171

NU116
Nucleoporin NUP116/NSP116

8

19

Small-scale

0.745

High

825172

DYL1
Dynein light chain 1, cytoplasmic

5

3

Small-scale

0.722

High

722003

XPO1
Exportin-1

5

20

Small-scale

0.712

High

825181

IMB1
Importin subunit beta-1

4

20

Small-scale

0.686

High

817836

GLE2
mRNA export factor GLE2

4

20

Small-scale

0.686

High

825153

NU159
Nucleoporin NUP159

3

18

Small-scale

0.651

High

825187

GLE1
mRNA export factor GLE1

3

11

Small-scale

0.650

High

795029

NU170
Nucleoporin NUP170

3

12

Small-scale

0.640

High

824725

MLP2
Protein MLP2

3

18

High-throughput

0.640

High

825166

NUP84
Nucleoporin NUP84

3

9

Small-scale

0.640

High

825170

NU100
Nucleoporin NUP100/NSP100

3

19

Small-scale

0.640

High

825191

MEX67
mRNA export factor MEX67

3

11

Small-scale

0.640

High

545134

SSB1
Ribosome-associated molecular chaperone SSB1

3

14

Small-scale

0.624

High

795393

ATG8
Autophagy-related protein 8

3

12

Small-scale

0.620

High

817795

NU157
Nucleoporin NUP157

2

12

High-throughput

0.614

High

526870

HSP72
Heat shock protein SSA2

2

15

Small-scale

0.611

High

782529

NU133
Nucleoporin NUP133

2

8

High-throughput

0.601

High

745768

GSP1
GTP-binding nuclear protein GSP1/CNR1

2

6

Small-scale

0.594

High

634247

NUP1
Nucleoporin NUP1

2

20

High-throughput

0.584

High

738538

NDC1
Nucleoporin NDC1

2

2

High-throughput

0.584

High

738861

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

4

Small-scale

0.584

High

758035

MTR2
mRNA transport regulator MTR2

2

4

Small-scale

0.584

High

825167

SEH1
Nucleoporin SEH1

2

20

High-throughput

0.584

High

825169

MLP1
Protein MLP1

2

20

High-throughput

0.584

High

825174

NUP53
Nucleoporin NUP53

2

7

High-throughput

0.584

High

825180

NUP59
Nucleoporin ASM4

2

7

High-throughput

0.584

High

825189

POM34
Nucleoporin POM34

2

3

High-throughput

0.584

High

524167

HSP71
Heat shock protein SSA1

2

15

Small-scale

0.571

High

818933

SSB2
Ribosome-associated molecular chaperone SSB2

2

14

Small-scale

0.571

High

548703

RNA1
Ran GTPase-activating protein 1

1

6

Small-scale

0.561

High

656494

KC11
Casein kinase I homolog 1

1

8

High-throughput

0.536

High

667096

CG22
G2/mitotic-specific cyclin-2

1

4

High-throughput

0.536

High

667137

CG23
G2/mitotic-specific cyclin-3

1

4

High-throughput

0.536

High

709398

HRR25
Casein kinase I homolog HRR25

1

8

High-throughput

0.536

High

825178

SXM1
Importin beta SMX1

1

20

Small-scale

0.515

High

745086

AFG2
ATPase family gene 2 protein

1

8

Small-scale

0.504

High

825158

BFA1
Mitotic check point protein BFA1

1

1

Small-scale

0.504

High

825175

ARX1
Probable metalloprotease ARX1

1

4

Small-scale

0.501

High

707292

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

734684

IMB3
Importin subunit beta-3

1

20

Small-scale

0.479

High

738478

NUP2
Nucleoporin NUP2

1

20

High-throughput

0.479

High

756631

NIC96
Nucleoporin NIC96

1

8

High-throughput

0.479

High

776522

NU120
Nucleoporin NUP120

1

4

High-throughput

0.479

High

779254

CENPA
Histone H3-like centromeric protein CSE4

1

18

High-throughput

0.479

High

803797

BRL1
Nucleus export protein BRL1

1

2

Small-scale

0.479

High

813409

PO152
Nucleoporin POM152

1

4

High-throughput

0.479

High

813632

NUP60
Nucleoporin NUP60

1

2

High-throughput

0.479

High

817875

IMB4
Importin subunit beta-4

1

20

Small-scale

0.479

High

825154

NUP85
Nucleoporin NUP85

1

5

High-throughput

0.479

High

825155

SAC3
Nuclear mRNA export protein SAC3

1

2

High-throughput

0.479

High

825156

NMD5
Nonsense-mediated mRNA decay protein 5

1

20

Small-scale

0.479

High

825157

NU192
Nucleoporin NUP192

1

8

High-throughput

0.479

High

825161

NUP57
Nucleoporin NUP57

1

19

High-throughput

0.479

High

825162

NUP42
Nucleoporin NUP42

1

17

High-throughput

0.479

High

825163

NU145
Nucleoporin NUP145

1

19

High-throughput

0.479

High

825164

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

13

High-throughput

0.479

High

825165

NU188
Nucleoporin NUP188

1

4

High-throughput

0.479

High

825168

NUP49
Nucleoporin NUP49/NSP49

1

19

High-throughput

0.479

High

825173

HEH2
Inner nuclear membrane protein HEH2

1

3

Small-scale

0.479

High

825179

SEC13
Protein transport protein SEC13

1

20

High-throughput

0.479

High

825185

YRA1
RNA annealing protein YRA1

1

7

High-throughput

0.479

High

825190

MTR10
mRNA transport regulator MTR10

1

20

Small-scale

0.479

High

825159

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

825176

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

825177

LRS4
Monopolin complex subunit LRS4

1

0

Small-scale

0.458

High

825186

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

392848

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.445

High

651946

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

4

High-throughput

0.445

High

741714

HSP7F
Heat shock protein homolog SSE1

1

18

High-throughput

0.445

High

804214

SSZ1
Ribosome-associated complex subunit SSZ1

1

7

High-throughput

0.445

High

825160

DPH4
Diphthamide biosynthesis protein 4

1

3

High-throughput

0.445

High

394625

EF1A
Elongation factor 1-alpha

1

2

Small-scale

0.437

High

748425

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

825182

AP3D
AP-3 complex subunit delta

1

13

High-throughput

0.437

High

825184

ATG9
Autophagy-related protein 9

1

2

High-throughput

0.437

High

806136

NMD3
60S ribosomal export protein NMD3

1

0

Small-scale

0.426

High

825183

CWC2
Pre-mRNA-splicing factor CWC2

1

1

High-throughput

0.417

High

810702

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.407

High

816240

HSP7E
Heat shock protein SSC3, mitochondrial

1

11

High-throughput

0.407

High

825188

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

597478

EF3A
Elongation factor 3A

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025