HitPredict

Interactor 1: SNP25 (P36975)
Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein)
Gene: Snap25

Interactor 2: STX5 (Q24509)
Syntaxin-5 (Sed5 protein) (dSed5)
Gene: Syx5

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0006887 - exocytosis GO:0006906 - vesicle fusion GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 212 Dm			1 467
+	Dm
		1098004 Q9VH76_DROME (9-212): 8.31e-65: 201: 70.19		STX5_DROME (1-451): 0: 517: 100.00
+	Hs
		893271 SNP25_HUMAN (10-211): 3.58e-61: 191: 61.39		STX5_HUMAN (123-450): 1.28e-73: 237: 50.92
+	Dm
		739422 SNP25_DROME (1-212): 5.23e-71: 216: 100.00		STX1A_DROME (160-467): 3e-64: 211: 14.56
+	Ce
		183449 O62414_CAEEL (10-211): 1.63e-62: 194: 57.35		STX1A_CAEEL (160-467): 1.04e-68: 222: 17.69
+	Hs
		893263 SNP25_HUMAN (10-211): 3.58e-61: 191: 61.39		STX1B_HUMAN (161-463): 1.21e-68: 222: 16.83
+	Dm
		1098103 Q9VH76_DROME (9-212): 8.31e-65: 201: 70.19		STX1A_DROME (160-467): 3e-64: 211: 14.56
+	Hs
		893278 SNP25_HUMAN (10-211): 3.58e-61: 191: 61.39		STX1A_HUMAN (161-463): 1.88e-67: 219: 16.17
+	Bt
		699168 SNP25_BOVIN (10-211): 3.58e-61: 191: 61.39		STX1A_BOVIN (161-463): 2.45e-67: 218: 16.17
+	Hs
		699251 SNP25_HUMAN (10-211): 3.58e-61: 191: 61.39		STX2_HUMAN (161-466): 1.53e-65: 214: 15.36
+	Dm
		739433 SNP25_DROME (1-212): 5.23e-71: 216: 100.00		Q9VR90_DROME (160-460): 9.92e-52: 180: 14.80
+	Hs
		893270 SNP25_HUMAN (10-211): 3.58e-61: 191: 61.39		STX4_HUMAN (161-466): 5.37e-57: 192: 17.74
+	Dm
		1366722 Q9VH76_DROME (9-212): 8.31e-65: 201: 70.19		Q9VR90_DROME (160-460): 9.92e-52: 180: 14.80
+	Dm
		739435 SNP25_DROME (1-212): 5.23e-71: 216: 100.00		Q9VU45_DROME (234-463): 4.64e-44: 158: 15.88
+	Ce
		248220 O62414_CAEEL (10-211): 1.63e-62: 194: 57.35		STX3_CAEEL (161-466): 1.53e-50: 175: 16.72
+	Hs
		893272 SNP25_HUMAN (10-211): 3.58e-61: 191: 61.39		STX3_HUMAN (161-447): 6.96e-52: 178: 14.58
+	Hs
		269404 SNP25_HUMAN (10-211): 3.58e-61: 191: 61.39		STX11_HUMAN (161-457): 2.29e-50: 174: 12.42
+	At
		1114737 SNP33_ARATH (14-211): 1.65e-60: 192: 26.57		SY111_ARATH (158-449): 9.15e-49: 171: 13.09
+	Dm
		1366725 Q9VH76_DROME (9-212): 8.31e-65: 201: 70.19		Q9VU45_DROME (234-463): 4.64e-44: 158: 15.88
+	At
		1351792 SNP33_ARATH (14-211): 1.65e-60: 192: 26.57		SY121_ARATH (182-449): 2.33e-46: 165: 13.31
+	Hs
		178460 SNP25_HUMAN (10-211): 3.58e-61: 191: 61.39		STX7_HUMAN (205-466): 3.46e-38: 141: 17.94