Interactor 1: FHR2 (P36980)
Complement factor H-related protein 2 (FHR-2) (DDESK59) (H factor-like 3) (H factor-like protein 2)
Gene: CFHR2

Interactor 2: FHR1 (Q03591)
Complement factor H-related protein 1 (FHR-1) (H factor-like protein 1) (FHL-1) (H-factor-like 1) (H36)
Gene: CFHR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Sushi~Sushi
Common GO terms GO:0001851 - complement component C3b binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006956 - complement activation
GO:0032091 - negative regulation of protein binding
and 2 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 270
Hs

1 330
+ Hs
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+ Hs
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+ Hs
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+ Dm

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Last updated: 15 Jul 2024