Protein: GIR2
Protein GIR2 (DRG family-regulatory protein 2) (Genetically interacts with ribosomal genes protein 2)

Gene: GIR2
Organism: Saccharomyces cerevisiae S288C
Interactions: 30
UniProt ID: Q03768

Gene Ontology (top 5):
GO:0001933 - negative regulation of protein phosphorylation
GO:0002181 - cytoplasmic translation
GO:0004860 - protein kinase inhibitor activity
GO:0005737 - cytoplasm
GO:0031333 - negative regulation of protein-containing complex assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919400

RBG2
Ribosome-interacting GTPase 2

11

6

Small-scale

0.759

High

813964

RBG1
Ribosome-interacting GTPase 1

4

6

Small-scale

0.695

High

755161

GCN1
eIF-2-alpha kinase activator GCN1

3

0

Small-scale

0.649

High

1044001

GIR2
Protein GIR2

1

0

High-throughput

0.631

High

579988

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

527568

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

722222

XPO1
Exportin-1

1

2

High-throughput

0.536

High

394865

EF1A
Elongation factor 1-alpha

2

0

Small-scale

0.528

High

546112

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

509702

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

599398

FUS3
Mitogen-activated protein kinase FUS3

1

0

High-throughput

0.480

High

656859

KC12
Casein kinase I homolog 2

1

0

High-throughput

0.480

High

1030247

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.480

High

1040418

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

0

High-throughput

0.480

High

393258

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

1044005

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.460

High

435331

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

525013

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

739457

ZUO1
Zuotin

1

2

High-throughput

0.445

High

453767

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

811488

XDJ1
DnaJ protein homolog XDJ1

1

0

High-throughput

0.426

High

863715

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

804074

VMA22
Vacuolar ATPase assembly protein VMA22

1

0

High-throughput

0.282

High

1044002

ISR1
Serine/threonine-protein kinase ISR1

1

0

High-throughput

0.282

High

824716

YIP2
Uncharacterized protein YIL152W

1

0

High-throughput

0.269

Low

708055

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

812619

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

1044003

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.249

Low

1044004

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025