HitPredict

Interactor 1: TGFR2 (P37173)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: TGFBR2

Interactor 2: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 567 Hs			1 208
+	Zm
		26108 A0A1D6IZ90_MAIZE (2-567): 1.24e-158: 469: 14.76		B4FRS1_MAIZE (11-208): 1.12e-91: 268: 72.28
+	Mm
		899110 TGFR2_MOUSE (1-567): 1.84e-148: 440: 92.24		RAB6B_MOUSE (1-208): 4.46e-87: 257: 100.00
+	At
		84860 Y5129_ARATH (14-560): 5.16e-144: 430: 14.52		RAH1C_ARATH (9-193): 3.8e-90: 265: 71.12
+	Hs
		592636 TGFR2_HUMAN (1-567): 1.25e-149: 443: 100.00		RAB6A_HUMAN (1-208): 1.37e-84: 250: 90.87
+	Hs
		1044945 AVR2B_HUMAN (69-565): 5.95e-135: 404: 33.79		RAB6B_HUMAN (1-208): 4.46e-87: 257: 100.00
+	Mm
		899109 ACVL1_MOUSE (128-543): 4.89e-122: 370: 31.92		RAB6B_MOUSE (1-208): 4.46e-87: 257: 100.00
+	Dm
		1279500 Q95SI0_DROME (56-542): 1.63e-120: 367: 31.35		RAB5_DROME (13-175): 6.17e-49: 160: 45.40
+	Dm
		1097876 Q24468_DROME (71-541): 2.06e-117: 359: 32.79		RAB5_DROME (13-175): 6.17e-49: 160: 45.40