HitPredict

Interactor 1: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Interactor 2: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.881

Property	Details
Experiments	12200120, 16554755, 37968396, 16429126
Identification Methods	cross-linking study, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 945 Sc			1 398
+	Rn
		312922 PSMD1_RAT (3-926): 0: 1114: 39.98		RD23B_RAT (2-398): 7.82e-92: 284: 27.50
+	Hs
		931703 PSMD1_HUMAN (3-926): 0: 1116: 39.98		RD23B_HUMAN (2-398): 5.12e-90: 279: 27.50
+	Hs
		931585 PSMD1_HUMAN (3-926): 0: 1116: 39.98		RD23A_HUMAN (2-398): 3.39e-87: 270: 28.09
+	Hs
		1404607 PSMD1_HUMAN (3-926): 0: 1116: 39.98		UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53
+	Hs
		1404601 PSMD1_HUMAN (3-926): 0: 1116: 39.98		UBQL2_HUMAN (1-373): 8.72e-55: 192: 12.65
+	Hs
		1404590 PSMD1_HUMAN (3-926): 0: 1116: 39.98		UBQL4_HUMAN (2-373): 1.17e-52: 186: 13.76
+	Hs
		987169 PSMD1_HUMAN (3-926): 0: 1116: 39.98		RS27A_HUMAN (2-89): 1.27e-38: 137: 22.73
+	Dm
		1464103 PSMD1_DROME (1-927): 0: 990: 36.04		Q9VWD9_DROME (2-374): 1.82e-47: 171: 13.38
+	Rn
		1194066 PSMD2_RAT (9-770): 0: 757: 17.31		RD23B_RAT (2-398): 7.82e-92: 284: 27.50
+	Hs
		931656 PSMD2_HUMAN (9-770): 0: 760: 17.31		RD23B_HUMAN (2-398): 5.12e-90: 279: 27.50
+	Hs
		931508 PSMD2_HUMAN (9-770): 0: 760: 17.31		RD23A_HUMAN (2-398): 3.39e-87: 270: 28.09
+	Hs
		1098165 PSMD2_HUMAN (9-770): 0: 760: 17.31		UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53
+	Hs
		1098159 PSMD2_HUMAN (9-770): 0: 760: 17.31		UBQL2_HUMAN (1-373): 8.72e-55: 192: 12.65
+	Hs
		1098150 PSMD2_HUMAN (9-770): 0: 760: 17.31		UBQL4_HUMAN (2-373): 1.17e-52: 186: 13.76
+	At
		1284089 PSD2A_ARATH (9-770): 0: 669: 17.76		RD23C_ARATH (2-398): 8.24e-89: 276: 25.62
+	Hs
		987007 PSMD2_HUMAN (9-770): 0: 760: 17.31		RS27A_HUMAN (2-89): 1.27e-38: 137: 22.73
+	Sp
		268138 RPN1_SCHPO (9-770): 0: 621: 18.33		RHP23_SCHPO (2-398): 4.2e-81: 255: 33.25
+	Dm
		1470298 Q9VW54_DROME (13-770): 0: 651: 17.61		Q9VCD5_DROME (2-398): 1.56e-52: 178: 20.55
+	Hs
		1154846 Q59EG8_HUMAN (9-770): 0: 756: 17.19		NEDD8_HUMAN (2-62): 2.69e-15: 72.3: 24.59
+	Dm
		1487629 Q9VW54_DROME (13-770): 0: 651: 17.61		Q9VWD9_DROME (2-374): 1.82e-47: 171: 13.38