Protein: RD23B
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)

Gene: RD23B, RAD23B
Organism: Homo sapiens
Interactions: 183
UniProt ID: P54727

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003684 - damaged DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

931651

XPC
DNA repair protein complementing XP-C cells

19

15

Small-scale

0.987

High

507727

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

13

20

Small-scale

0.980

High

931634

PSMD4
26S proteasome non-ATPase regulatory subunit 4

8

20

Small-scale

0.969

High

931720

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

7

20

Small-scale

0.965

High

926898

ATX3
Ataxin-3

5

5

Small-scale

0.926

High

778642

PRS7
26S proteasome regulatory subunit 7

5

20

Small-scale

0.922

High

931655

UBE3A
Ubiquitin-protein ligase E3A

4

20

Small-scale

0.906

High

931670

DDI2
Protein DDI1 homolog 2

4

19

High-throughput

0.892

High

931729

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

3

18

Small-scale

0.847

High

931719

UBQL2
Ubiquilin-2

3

20

High-throughput

0.843

High

507127

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

3

20

Small-scale

0.836

High

138034

PSDE
26S proteasome non-ATPase regulatory subunit 14

3

20

Small-scale

0.827

High

931663

PSMD6
26S proteasome non-ATPase regulatory subunit 6

3

20

Small-scale

0.827

High

931701

UBL7
Ubiquitin-like protein 7

2

4

High-throughput

0.811

High

931665

ADRM1
Proteasomal ubiquitin receptor ADRM1

2

12

Small-scale

0.806

High

851275

PRS6B
26S proteasome regulatory subunit 6B

2

20

High-throughput

0.789

High

130931

HIP1
Huntingtin-interacting protein 1

2

6

High-throughput

0.783

High

931679

TAXB1
Tax1-binding protein 1

2

19

High-throughput

0.783

High

931718

MKRN1
E3 ubiquitin-protein ligase makorin-1

2

2

High-throughput

0.783

High

931703

PSMD1
26S proteasome non-ATPase regulatory subunit 1

2

20

Small-scale

0.776

High

931697

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

9

8

Small-scale

0.754

High

241199

PRKN
E3 ubiquitin-protein ligase parkin

2

20

Small-scale

0.754

High

906486

PSMD7
26S proteasome non-ATPase regulatory subunit 7

2

20

Small-scale

0.754

High

931641

PRS8
26S proteasome regulatory subunit 8

2

20

Small-scale

0.754

High

931642

PRS10
26S proteasome regulatory subunit 10B

2

20

Small-scale

0.754

High

931646

H31
Histone H3.1

2

18

High-throughput

0.754

High

931656

PSMD2
26S proteasome non-ATPase regulatory subunit 2

2

20

Small-scale

0.754

High

931716

HDAC6
Protein deacetylase HDAC6

2

9

Small-scale

0.754

High

931671

OTUD1
OTU domain-containing protein 1

2

7

Small-scale

0.705

High

132457

CDC7
Cell division cycle 7-related protein kinase

1

11

High-throughput

0.691

High

625266

CSK22
Casein kinase II subunit alpha'

1

10

High-throughput

0.691

High

724674

MK04
Mitogen-activated protein kinase 4

1

9

High-throughput

0.691

High

877073

KC1D
Casein kinase I isoform delta

1

5

High-throughput

0.691

High

897180

CDK7
Cyclin-dependent kinase 7

1

8

High-throughput

0.691

High

931667

MK06
Mitogen-activated protein kinase 6

1

8

High-throughput

0.691

High

832886

CETN2
Centrin-2

4

7

Small-scale

0.689

High

303079

ZFAN5
AN1-type zinc finger protein 5

2

4

Small-scale

0.687

High

931699

PNMA5
Paraneoplastic antigen-like protein 5

3

5

High-throughput

0.675

High

931721

PUF60
Poly(U)-binding-splicing factor PUF60

3

12

High-throughput

0.675

High

798898

BRCA1
Breast cancer type 1 susceptibility protein

1

17

Small-scale

0.665

High

853450

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

20

Small-scale

0.665

High

931705

SH3G3
Endophilin-A3

2

13

High-throughput

0.659

High

931636

SEM1
26S proteasome complex subunit SEM1

3

5

Small-scale

0.650

High

131859

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

20

Small-scale

0.647

High

326937

UBE4B
Ubiquitin conjugation factor E4 B

2

9

High-throughput

0.628

High

931707

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

2

4

High-throughput

0.628

High

846732

GRK6
G protein-coupled receptor kinase 6

1

9

High-throughput

0.618

High

931680

MYLK4
Myosin light chain kinase family member 4

1

13

High-throughput

0.618

High

386454

SPTA1
Spectrin alpha chain, erythrocytic 1

1

15

Small-scale

0.618

High

400535

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.618

High

418899

H2A1B
Histone H2A type 1-B/E

1

20

High-throughput

0.618

High

425401

ISG15
Ubiquitin-like protein ISG15

1

20

Small-scale

0.618

High

591554

H2AX
Histone H2AX

1

20

High-throughput

0.618

High

610278

PRS6A
26S proteasome regulatory subunit 6A

1

20

High-throughput

0.618

High

647513

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

9

Small-scale

0.618

High

754772

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

769830

RFC2
Replication factor C subunit 2

1

2

High-throughput

0.618

High

929854

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

19

High-throughput

0.618

High

931477

RD23A
UV excision repair protein RAD23 homolog A

1

20

Small-scale

0.618

High

931633

RD23B
UV excision repair protein RAD23 homolog B

1

19

High-throughput

0.618

High

931635

TERA
Transitional endoplasmic reticulum ATPase

1

19

High-throughput

0.618

High

931638

UBC12
NEDD8-conjugating enzyme Ubc12

1

20

High-throughput

0.618

High

931640

PRS4
26S proteasome regulatory subunit 4

1

20

High-throughput

0.618

High

931644

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.618

High

931650

H33
Histone H3.3

1

18

High-throughput

0.618

High

931652

EWS
RNA-binding protein EWS

1

9

High-throughput

0.618

High

931657

BIRC3
Baculoviral IAP repeat-containing protein 3

1

10

High-throughput

0.618

High

931661

HLTF
Helicase-like transcription factor

1

4

High-throughput

0.618

High

931677

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

20

High-throughput

0.618

High

931683

YAF2
YY1-associated factor 2

1

2

High-throughput

0.618

High

931686

UBA3
NEDD8-activating enzyme E1 catalytic subunit

1

11

Small-scale

0.618

High

931689

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

18

High-throughput

0.618

High

931693

OPTN
Optineurin

1

17

High-throughput

0.618

High

931695

RN185
E3 ubiquitin-protein ligase RNF185

1

20

Small-scale

0.618

High

931704

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.618

High

931714

PD1L1
Programmed cell death 1 ligand 1

1

7

High-throughput

0.618

High

931717

ZRAN1
Ubiquitin thioesterase ZRANB1

1

16

High-throughput

0.618

High

931727

FND3A
Fibronectin type-III domain-containing protein 3A

1

6

High-throughput

0.618

High

210901

PSMD3
26S proteasome non-ATPase regulatory subunit 3

2

12

High-throughput

0.611

High

931648

PO6F2
POU domain, class 6, transcription factor 2

2

3

High-throughput

0.606

High

931690

RSCA1
Regulatory solute carrier protein family 1 member 1

2

1

High-throughput

0.606

High

931687

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.586

High

128186

PSD12
26S proteasome non-ATPase regulatory subunit 12

2

20

Small-scale

0.584

High

259682

BRD4
Bromodomain-containing protein 4

2

5

High-throughput

0.584

High

681133

PSA2
Proteasome subunit alpha type-2

2

20

Small-scale

0.584

High

681308

PSA3
Proteasome subunit alpha type-3

2

20

Small-scale

0.584

High

887628

PSB2
Proteasome subunit beta type-2

2

20

Small-scale

0.584

High

931643

H4
Histone H4

2

7

High-throughput

0.584

High

931653

PO5F1
POU domain, class 5, transcription factor 1

2

3

Small-scale

0.584

High

931710

WDR76
WD repeat-containing protein 76

2

9

High-throughput

0.584

High

325754

UBR5
E3 ubiquitin-protein ligase UBR5

1

20

High-throughput

0.575

High

501947

H2AZ
Histone H2A.Z

1

20

Small-scale

0.575

High

919834

PLK1
Serine/threonine-protein kinase PLK1

1

12

Small-scale

0.575

High

931713

RNF12
E3 ubiquitin-protein ligase RLIM

1

20

High-throughput

0.575

High

931700

BTBD9
BTB/POZ domain-containing protein 9

2

11

High-throughput

0.574

High

931728

KCTD3
BTB/POZ domain-containing protein KCTD3

2

6

High-throughput

0.574

High

395755

ESR1
Estrogen receptor

2

15

High-throughput

0.571

High

931674

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.553

High

931682

TRI59
Tripartite motif-containing protein 59

1

16

Small-scale

0.553

High

767791

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.536

High

931649

CBX1
Chromobox protein homolog 1

1

7

High-throughput

0.536

High

931666

MEA1
Male-enhanced antigen 1

1

1

High-throughput

0.536

High

931681

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

931709

MED20
Mediator of RNA polymerase II transcription subunit 20

1

2

High-throughput

0.536

High

931723

PPCT
Phosphatidylcholine transfer protein

1

1

High-throughput

0.536

High

105639

APRIO
Alternative prion protein

2

2

High-throughput

0.533

High

474575

VIME
Vimentin

1

5

Small-scale

0.515

High

931645

EF1A1
Elongation factor 1-alpha 1

1

4

Small-scale

0.515

High

931673

PAQR3
Progestin and adipoQ receptor family member 3

1

3

Small-scale

0.512

High

280407

DEAF1
Deformed epidermal autoregulatory factor 1 homolog

1

1

High-throughput

0.508

High

827360

MLH1
DNA mismatch repair protein Mlh1

1

1

Small-scale

0.508

High

185558

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

5

High-throughput

0.501

High

481174

HMGB1
High mobility group protein B1

1

2

Small-scale

0.501

High

662311

PAX3
Paired box protein Pax-3

1

0

Small-scale

0.480

High

695031

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

Small-scale

0.480

High

123354

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

2

High-throughput

0.479

High

127911

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

20

High-throughput

0.479

High

128888

MEN1
Menin

1

1

High-throughput

0.479

High

165298

PSA7
Proteasome subunit alpha type-7

1

20

High-throughput

0.479

High

215278

TXNL1
Thioredoxin-like protein 1

1

7

High-throughput

0.479

High

295477

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

5

High-throughput

0.479

High

315332

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.479

High

371564

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

411648

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.479

High

468216

HS90B
Heat shock protein HSP 90-beta

1

11

High-throughput

0.479

High

536827

HSP7C
Heat shock cognate 71 kDa protein

1

12

High-throughput

0.479

High

567320

TCTP
Translationally-controlled tumor protein

1

3

High-throughput

0.479

High

622784

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

4

Small-scale

0.479

High

633640

PSB1
Proteasome subunit beta type-1

1

20

High-throughput

0.479

High

680824

PSA1
Proteasome subunit alpha type-1

1

20

High-throughput

0.479

High

681606

PSA4
Proteasome subunit alpha type-4

1

20

High-throughput

0.479

High

700591

PSA5
Proteasome subunit alpha type-5

1

20

High-throughput

0.479

High

700857

PSB4
Proteasome subunit beta type-4

1

20

High-throughput

0.479

High

701005

PSB6
Proteasome subunit beta type-6

1

20

High-throughput

0.479

High

701123

PSB5
Proteasome subunit beta type-5

1

20

High-throughput

0.479

High

744646

TF2H1
General transcription factor IIH subunit 1

1

3

Small-scale

0.479

High

832680

BCL6
B-cell lymphoma 6 protein

1

3

High-throughput

0.479

High

872111

SOX2
Transcription factor SOX-2

1

3

Small-scale

0.479

High

874134

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

9

High-throughput

0.479

High

887501

PSB3
Proteasome subunit beta type-3

1

20

High-throughput

0.479

High

931637

PSA6
Proteasome subunit alpha type-6

1

20

High-throughput

0.479

High

931654

TF65
Transcription factor p65

1

8

High-throughput

0.479

High

931659

TRI14
Tripartite motif-containing protein 14

1

11

High-throughput

0.479

High

931660

FAK2
Protein-tyrosine kinase 2-beta

1

1

High-throughput

0.479

High

931664

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

3

High-throughput

0.479

High

931668

HIF1A
Hypoxia-inducible factor 1-alpha

1

1

Small-scale

0.479

High

931669

CDKN3
Cyclin-dependent kinase inhibitor 3

1

1

High-throughput

0.479

High

931672

ECM29
Proteasome adapter and scaffold protein ECM29

1

7

High-throughput

0.479

High

931675

SEML
Putative protein SEM1, isoform 2

1

2

High-throughput

0.479

High

931678

SLN11
Schlafen family member 11

1

1

Small-scale

0.479

High

931684

CGAS
Cyclic GMP-AMP synthase

1

5

High-throughput

0.479

High

931691

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

931698

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

931702

PSB7
Proteasome subunit beta type-7

1

20

High-throughput

0.479

High

931711

NANOG
Homeobox protein NANOG

1

5

High-throughput

0.479

High

931715

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

5

High-throughput

0.479

High

931722

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

Small-scale

0.479

High

931725

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

16

High-throughput

0.479

High

450331

ACBP
Acyl-CoA-binding protein

1

6

High-throughput

0.464

High

577420

ETS1
Protein C-ets-1

1

0

High-throughput

0.458

High

617667

XRCC1
DNA repair protein XRCC1

1

0

Small-scale

0.458

High

931658

TDG
G/T mismatch-specific thymine DNA glycosylase

1

0

Small-scale

0.458

High

931708

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

931712

PHP14
14 kDa phosphohistidine phosphatase

1

0

High-throughput

0.458

High

529418

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.445

High

563478

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.445

High

931639

RHOA
Transforming protein RhoA

1

8

High-throughput

0.445

High

931647

S35B1
Solute carrier family 35 member B1

1

5

High-throughput

0.445

High

931706

UBXN6
UBX domain-containing protein 6

1

2

Small-scale

0.445

High

181616

CETN3
Centrin-3

1

9

Small-scale

0.437

High

931688

SSH1
Protein phosphatase Slingshot homolog 1

1

5

High-throughput

0.437

High

931696

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

931724

COR1C
Coronin-1C

1

4

Small-scale

0.437

High

404743

PRIO
Major prion protein

1

0

High-throughput

0.426

High

886676

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.408

High

931662

MFS10
Major facilitator superfamily domain-containing protein 10

1

6

High-throughput

0.407

High

931676

NIPA1
Magnesium transporter NIPA1

1

3

High-throughput

0.407

High

931685

MFSD9
Major facilitator superfamily domain-containing protein 9

1

6

High-throughput

0.407

High

931692

S35B4
Nucleotide sugar transporter SLC35B4

1

5

High-throughput

0.407

High

931726

S35A3
UDP-N-acetylglucosamine transporter

1

3

High-throughput

0.407

High

931694

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

614668

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025