HitPredict

Interactor 1: NUP62 (P37198)
Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62)
Gene: NUP62

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 1 others more... GO:0006606 - protein import into nucleus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 522 Hs			1 216
+	Hs
		846737 SMCA2_HUMAN (35-457): 2.46e-53: 196: 11.57		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		297829 K0754_HUMAN (1-362): 1.29e-27: 120: 12.09		RAB35_HUMAN (6-188): 1.31e-87: 258: 29.19
+	Sc
		541858 NSP1_YEAST (30-504): 3.31e-29: 124: 16.02		GSP1_YEAST (1-214): 5.23e-83: 247: 80.56
+	Sc
		698833 NU159_YEAST (2-325): 1.43e-17: 88.6: 15.17		GSP1_YEAST (1-214): 5.23e-83: 247: 80.56
+	Hs
		857959 NUP98_HUMAN (2-334): 2.75e-13: 75.1: 16.39		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00