HitPredict

Interactor 1: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Interactor 2: CUZ1 (P53899)
CDC48-associated ubiquitin-like/zinc finger protein 1 (CDC48-associated UBL/Zn-finger protein 1)
Gene: CUZ1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	37968396, 24297164
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 945 Sc			1 274
+	Hs
		1349666 PSMD1_HUMAN (3-926): 0: 1116: 39.98		ZFAN1_HUMAN (12-239): 2.68e-92: 275: 27.08
+	Mm
		1189655 PSMD1_MOUSE (3-926): 0: 1117: 40.39		ZFN2A_MOUSE (13-136): 2.4e-31: 116: 16.36
+	Hs
		1329563 PSMD1_HUMAN (3-926): 0: 1116: 39.98		ZFN2A_HUMAN (13-99): 1.83e-30: 112: 16.41
+	Mm
		1353978 PSMD2_MOUSE (9-770): 0: 757: 17.31		ZFN2A_MOUSE (13-136): 2.4e-31: 116: 16.36
+	Hs
		1098059 PSMD2_HUMAN (9-770): 0: 760: 17.31		ZFN2A_HUMAN (13-99): 1.83e-30: 112: 16.41
+	Hs
		1098072 PSMD2_HUMAN (9-770): 0: 760: 17.31		ZFN2B_HUMAN (13-100): 8.06e-27: 106: 14.73
+	Sc
		803639 RPN1_YEAST (9-573): 1.14e-134: 430: 17.33		CUZ1_YEAST (1-274): 1.66e-136: 387: 100.00