Protein: CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1 (CDC48-associated UBL/Zn-finger protein 1)

Gene: CUZ1
Organism: Saccharomyces cerevisiae S288C
Interactions: 77
UniProt ID: P53899

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0035617 - stress granule disassembly
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

679935

CDC48
Cell division control protein 48

5

2

Small-scale

0.721

High

757897

UBX1
UBX domain-containing protein 1

3

0

Small-scale

0.633

High

509671

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

4

Small-scale

0.629

High

645962

DBF2
Cell cycle protein kinase DBF2

2

1

Small-scale

0.602

High

754442

NPL4
Nuclear protein localization protein 4

2

1

Small-scale

0.601

High

740201

RPN2
26S proteasome regulatory subunit RPN2

2

7

Small-scale

0.595

High

924464

RPN8
26S proteasome regulatory subunit RPN8

2

2

Small-scale

0.595

High

750877

PRS6B
26S proteasome regulatory subunit 6B homolog

2

7

Small-scale

0.584

High

817078

RPN3
26S proteasome regulatory subunit RPN3

2

2

Small-scale

0.584

High

924462

RPN7
26S proteasome regulatory subunit RPN7

2

5

Small-scale

0.584

High

924468

RPN5
26S proteasome regulatory subunit RPN5

2

5

Small-scale

0.584

High

805984

RT107
Regulator of Ty1 transposition protein 107

1

0

High-throughput

0.493

High

816531

SNU13
13 kDa ribonucleoprotein-associated protein

1

0

High-throughput

0.493

High

656830

KC12
Casein kinase I homolog 2

1

0

High-throughput

0.480

High

672199

KIN82
Serine/threonine-protein kinase KIN82

1

0

High-throughput

0.480

High

735532

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.480

High

801182

SIC1
Protein SIC1

1

0

Small-scale

0.480

High

801885

KSP1
Serine/threonine-protein kinase KSP1

1

0

High-throughput

0.480

High

924455

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.480

High

750745

PRS6A
26S proteasome regulatory subunit 6A

1

9

High-throughput

0.479

High

750984

PRS7
26S proteasome regulatory subunit 7 homolog

1

12

High-throughput

0.479

High

803639

RPN1
26S proteasome regulatory subunit RPN1

1

7

High-throughput

0.479

High

822422

PRS4
26S proteasome regulatory subunit 4 homolog

1

8

High-throughput

0.479

High

850130

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

3

Small-scale

0.479

High

893068

PSD10
Probable 26S proteasome regulatory subunit p28

1

1

High-throughput

0.479

High

918101

RPN14
26S proteasome regulatory subunit RPN14

1

1

High-throughput

0.479

High

921089

PRS10
26S proteasome subunit RPT4

1

11

High-throughput

0.479

High

924456

PRS8
26S proteasome regulatory subunit 8 homolog

1

9

High-throughput

0.479

High

924469

RPN6
26S proteasome regulatory subunit RPN6

1

4

High-throughput

0.479

High

150301

RPN13
26S proteasome regulatory subunit RPN13

1

0

High-throughput

0.458

High

314899

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.458

High

402072

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

450625

FAS1
Fatty acid synthase subunit beta

1

0

Small-scale

0.458

High

470568

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

Small-scale

0.458

High

471425

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

Small-scale

0.458

High

479694

F16P
Fructose-1,6-bisphosphatase

1

0

Small-scale

0.458

High

518356

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.458

High

632192

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

Small-scale

0.458

High

645195

PSB4
Proteasome subunit beta type-4

1

0

Small-scale

0.458

High

663321

FPS1
Glycerol uptake/efflux facilitator protein

1

0

Small-scale

0.458

High

694609

SPT5
Transcription elongation factor SPT5

1

0

Small-scale

0.458

High

707838

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

738332

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.458

High

743826

FRDS
Fumarate reductase 1

1

0

Small-scale

0.458

High

804784

NADE
Glutamine-dependent NAD(+) synthetase

1

0

Small-scale

0.458

High

806784

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

820509

RGI2
Respiratory growth induced protein 2

1

0

Small-scale

0.458

High

850332

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

0

High-throughput

0.458

High

919578

YG5B
Uncharacterized RNA-binding protein YGR250C

1

0

Small-scale

0.458

High

921070

SPC98
Spindle pole body component SPC98

1

0

High-throughput

0.458

High

924454

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

0

Small-scale

0.458

High

924457

YM44
Uncharacterized protein YMR178W

1

0

High-throughput

0.458

High

924458

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

924459

RPN9
26S proteasome regulatory subunit RPN9

1

0

High-throughput

0.458

High

924460

UBX2
UBX domain-containing protein 2

1

0

Small-scale

0.458

High

924461

DCE
Glutamate decarboxylase

1

0

Small-scale

0.458

High

924465

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

924466

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

924467

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.458

High

924470

HAA1
Transcriptional activator HAA1

1

0

High-throughput

0.458

High

524777

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

527369

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

545823

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

819443

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

808969

HXT6
High-affinity hexose transporter HXT6

1

1

Small-scale

0.437

High

808993

HXT7
High-affinity hexose transporter HXT7

1

1

Small-scale

0.437

High

358303

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

359314

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

836831

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

670195

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.269

Low

382973

RMAR
Small ribosomal subunit protein uS3m

1

0

Small-scale

0.249

Low

534193

PCKA
Phosphoenolpyruvate carboxykinase

1

0

Small-scale

0.249

Low

715045

ERG9
Squalene synthase ERG9

1

0

Small-scale

0.249

Low

810866

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.249

Low

812544

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

924463

YD071
Putative uncharacterized protein YDL071C

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025