HitPredict

Interactor 1: THB (P37242)
Thyroid hormone receptor beta (Nuclear receptor subfamily 1 group A member 2) (c-erbA-2) (c-erbA-beta)
Gene: Thrb

Interactor 2: Q8BK32 (Q8BK32)
Nuclear receptor corepressor 1
Gene: Ncor1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	21389087, 19052228
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 461 Mm			1 291
+	Hs
		261383 THB_HUMAN (1-461): 6.66e-147: 428: 96.53		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		500510 THB_HUMAN (1-461): 6.66e-147: 428: 96.53		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		261399 RXRA_HUMAN (2-460): 1.91e-124: 371: 21.28		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Mm
		723171 PPARD_MOUSE (77-461): 1.55e-118: 355: 26.98		NCOR1_MOUSE (1-290): 7.91e-134: 420: 92.76
+	Hs
		261481 PPARA_HUMAN (71-461): 1.15e-115: 349: 27.16		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		261450 NR1H2_HUMAN (6-460): 1.03e-114: 346: 24.47		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		261474 PPARD_HUMAN (87-461): 6.17e-115: 346: 27.92		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		587211 RXRA_HUMAN (2-460): 1.91e-124: 371: 21.28		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		261493 NR1H3_HUMAN (11-460): 1.61e-114: 345: 27.41		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		261381 RARA_HUMAN (5-461): 5.98e-114: 344: 29.32		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		818890 RXRG_HUMAN (1-460): 2.22e-123: 368: 22.39		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Xl
		574911 THBA_XENLA (89-461): 6.51e-126: 372: 91.96		NCOR1_XENLA (1-290): 2.65e-116: 369: 71.72
+	Hs
		992457 PPARA_HUMAN (71-461): 1.15e-115: 349: 27.16		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		874405 NR1H2_HUMAN (6-460): 1.03e-114: 346: 24.47		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		975486 PPARD_HUMAN (87-461): 6.17e-115: 346: 27.92		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		1025275 NR1H3_HUMAN (11-460): 1.61e-114: 345: 27.41		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		488042 RARA_HUMAN (5-461): 5.98e-114: 344: 29.32		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Mm
		509327 RARA_MOUSE (5-461): 7.93e-114: 344: 28.88		Q8BK32_MOUSE (1-291): 4.73e-135: 385: 100.00
+	Xl
		546248 THAA_XENLA (81-461): 2.07e-119: 357: 81.89		Q1W3Z6_XENLA (4-290): 1.92e-116: 370: 51.21
+	Xl
		546251 THAA_XENLA (81-461): 2.07e-119: 357: 81.89		NCOR1_XENLA (1-290): 2.65e-116: 369: 71.72