HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: EDC4 (Q6P2E9)
Enhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls)
Gene: EDC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31980649, 36634849, unassigned2173
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1401
+	Hs
		742612 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		MACF1_HUMAN (908-1276): 1.45e-46: 186: 10.59
+	Hs
		742235 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		DYST_HUMAN (950-1290): 2.23e-12: 74.4: 11.29
+	Hs
		742470 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		CHAP1_HUMAN (435-998): 6.58e-12: 72.5: 9.91
+	Hs
		742639 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		PCLO_HUMAN (526-984): 9.34e-12: 72.5: 8.35