HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: CNN2 (Q99439)
Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Gene: CNN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36634849
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005576 - extracellular region GO:0015629 - actin cytoskeleton GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 309
+	Hs
		742311 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		CNN3_HUMAN (4-306): 3.73e-147: 418: 65.48
+	Hs
		742590 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		TAGL3_HUMAN (7-190): 3.75e-73: 225: 41.33
+	Hs
		741836 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		TAGL2_HUMAN (7-190): 6.41e-72: 222: 42.35
+	Hs
		742228 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		TAGL_HUMAN (7-192): 4.25e-71: 220: 37.19
+	Hs
		742283 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		IQGA2_HUMAN (6-138): 1.4e-37: 144: 17.24