HitPredict

Interactor 1: DNLI1 (P37913)
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)
Gene: Lig1

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 916 Mm			1 441
+	Hs
		267957 DNLI3_HUMAN (152-903): 0: 577: 23.11		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1194744 Q80ZH7_MOUSE (152-903): 0: 576: 23.11		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		836861 DNLI4_HUMAN (274-914): 0: 554: 21.07		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		268143 NIPBL_HUMAN (1-308): 5.87e-22: 105: 13.55		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1154100 NIPBL_MOUSE (1-283): 7.43e-20: 98.1: 13.51		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268089 MDC1_HUMAN (7-355): 1.01e-09: 65.1: 9.55		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		1035129 MYO9B_HUMAN (26-276): 7.43e-26: 117: 16.48		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1192155 HUWE1_HUMAN (10-378): 2.59e-21: 102: 12.66		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1281478 MACF1_HUMAN (330-549): 3.2e-20: 99.3: 14.48		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		903607 MACF1_HUMAN (330-549): 3.2e-20: 99.3: 14.48		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		1192257 HUWE1_HUMAN (10-378): 2.59e-21: 102: 12.66		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97
+	Hs
		1056932 MDC1_HUMAN (7-355): 1.01e-09: 65.1: 9.55		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		1264784 TITIN_HUMAN (14-293): 2.66e-09: 63.8: 11.90		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29