HitPredict

Interactor 1: HSP68 (O97125)
Heat shock protein 68
Gene: HSP68

Interactor 2: HSP22 (P02515)
Heat shock protein 22
Gene: HSP22

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008340 - determination of adult lifespan GO:0042026 - protein refolding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 635 Dm			1 174
+	Dm
		356609 HSP68_DROME (1-635): 0: 954: 100.00		HSP23_DROME (1-174): 7.38e-52: 165: 34.62
+	Dm
		384758 HSP71_DROME (1-635): 0: 941: 80.84		HSP22_DROME (1-174): 1.29e-55: 174: 100.00
+	Dm
		384762 HSP70_DROME (1-635): 0: 941: 80.84		HSP22_DROME (1-174): 1.29e-55: 174: 100.00
+	Dm
		384771 HSP72_DROME (1-635): 0: 941: 81.12		HSP22_DROME (1-174): 1.29e-55: 174: 100.00
+	Dm
		384792 HSP71_DROME (1-635): 0: 941: 80.84		HSP23_DROME (1-174): 7.38e-52: 165: 34.62
+	Dm
		384798 HSP70_DROME (1-635): 0: 941: 80.84		HSP23_DROME (1-174): 7.38e-52: 165: 34.62
+	Hs
		415301 HSP7C_HUMAN (2-609): 0: 943: 73.44		HSPB1_HUMAN (4-173): 8.15e-45: 148: 25.58
+	Dm
		356610 HSP68_DROME (1-635): 0: 954: 100.00		HSP27_DROME (10-173): 6.97e-39: 133: 29.55
+	Hs
		384615 HSP7C_HUMAN (2-609): 0: 943: 73.44		CRYAB_HUMAN (8-167): 1.79e-43: 144: 26.71
+	Dm
		384885 HSP71_DROME (1-635): 0: 941: 80.84		HSP26_DROME (42-172): 2.33e-42: 142: 35.61
+	Dm
		384894 HSP70_DROME (1-635): 0: 941: 80.84		HSP26_DROME (42-172): 2.33e-42: 142: 35.61
+	Dm
		384974 HSP71_DROME (1-635): 0: 941: 80.84		HSP27_DROME (10-173): 6.97e-39: 133: 29.55
+	Dm
		384983 HSP70_DROME (1-635): 0: 941: 80.84		HSP27_DROME (10-173): 6.97e-39: 133: 29.55
+	Dm
		384995 HSP72_DROME (1-635): 0: 941: 81.12		HSP27_DROME (10-173): 6.97e-39: 133: 29.55
+	Dm
		385006 HSP74_DROME (1-635): 0: 940: 80.97		HSP27_DROME (10-173): 6.97e-39: 133: 29.55
+	Hs
		1198801 Q53FC7_HUMAN (3-635): 0: 942: 68.45		HSPB8_HUMAN (2-141): 3.66e-33: 118: 22.88
+	Mm
		989277 HSP7C_MOUSE (2-609): 0: 942: 73.44		HSPB2_MOUSE (8-138): 6.42e-31: 112: 21.97