Interactor 1: CDC27 (P38042)
Anaphase-promoting complex subunit CDC27 (Anaphase-promoting complex subunit 3) (Cell division control protein 27)
Gene: CDC27

Interactor 2: APC10 (P53068)
Anaphase-promoting complex subunit DOC1 (Destruction of cyclin B protein 1)
Gene: DOC1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.961

The method score is based on:

Property Details
Experiments 21186364, 9348530, 12609981, 16554755, 37968396, 10318877, 9469814
Identification Methods cross-linking study, cosedimentation through density gradient, affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC10~TPR_1, ANAPC10~TPR_8
Common GO terms GO:0005680 - anaphase-promoting complex
GO:0007346 - regulation of mitotic cell cycle
GO:0016567 - protein ubiquitination
GO:0031145 - anaphase-promoting complex-dependent catabolic process
GO:0051301 - cell division
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 758
Sc

1 250
+ At
+ At
+ Sc
+ At
+ Sp
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024