Interactor 1: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Interactor 2: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 11805826, 30568249, 31511893, 25877921, 16429126, 16449635, unassigned1262
Identification Methods tandem affinity purification, affinity chromatography technology, two hybrid, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~DUF4217, DEAD~Helicase_C, DUF4217~Helicase_C, Helicase_C~Helicase_C
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005730 - nucleolus
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 773
Sc

1 505
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Dm
+ Dm
+ Hs
+ Dm

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Last updated: 15 Jul 2024