HitPredict

Interactor 1: SWD3 (P38123)
COMPASS component SWD3 (Complex proteins associated with SET1 protein SWD3) (Set1C component SWD3)
Gene: SWD3

Interactor 2: SWD1 (P39706)
COMPASS component SWD1 (Complex proteins associated with SET1 protein SWD1) (Set1C component SWD1)
Gene: SWD1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.976

Property	Details
Experiments	11742990, 10688190, 11805826, 22147691, 16554755, 16429126, 30100181, 18342605, 37968396, 21179020
Identification Methods	coimmunoprecipitation, two hybrid, tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0000723 - telomere maintenance GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0031509 - subtelomeric heterochromatin formation GO:0048188 - Set1C/COMPASS complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 315 Sc			1 426
+	Dr
		1193337 Q7ZTX2_DANRE (91-314): 2.13e-58: 192: 26.11		Q7ZUU9_DANRE (1-397): 7.04e-78: 252: 28.15
+	Hs
		903242 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		RBBP5_HUMAN (1-397): 2.09e-78: 254: 28.15
+	Mm
		903670 WDR5_MOUSE (4-216): 3.22e-55: 184: 19.09		RBBP5_MOUSE (1-397): 4.12e-78: 253: 28.15
+	Hs
		1240442 POC1B_HUMAN (40-311): 9.25e-73: 233: 21.82		POC1A_HUMAN (157-426): 6.52e-44: 159: 9.63
+	Hs
		254111 FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91		WDR1_HUMAN (10-250): 8.34e-37: 143: 24.10
+	Hs
		903418 FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91		WDR5_HUMAN (245-419): 2.37e-22: 98.8: 11.74
+	Hs
		1103007 FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91		SMU1_HUMAN (13-340): 3.07e-20: 94.9: 17.16
+	Sp
		999842 TUP12_SCHPO (87-312): 1.26e-47: 170: 21.37		TUP11_SCHPO (152-425): 2.83e-43: 161: 12.72
+	Hs
		792949 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		LIS1_HUMAN (210-422): 6.1e-33: 130: 9.86
+	Hs
		903428 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42
+	Hs
		1281292 FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91		FBXW7_HUMAN (3-95): 3.57e-11: 67.2: 14.43
+	Hs
		903551 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		NLE1_HUMAN (243-415): 3.68e-22: 100: 10.92
+	Hs
		903077 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		WDR5_HUMAN (245-419): 2.37e-22: 98.8: 11.74
+	Hs
		903521 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		WDR26_HUMAN (4-340): 4.17e-21: 98: 16.72
+	Hs
		903349 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		WDR5B_HUMAN (245-426): 4.38e-21: 95.3: 13.19
+	Ca
		483033 TUP1_CANAL (2-216): 6.36e-56: 190: 21.46		TUP1_CANAL (3-103): 7.94e-15: 78: 16.19
+	Hs
		196984 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		PRP4_HUMAN (243-405): 2.82e-12: 70.3: 12.28
+	Hs
		196910 PRP4_HUMAN (94-313): 5.33e-43: 156: 13.97		PRP4_HUMAN (243-405): 2.82e-12: 70.3: 12.28