HitPredict

Interactor 1: ISW1 (P38144)
ISWI chromatin-remodeling complex ATPase ISW1 (EC 3.6.4.-)
Gene: ISW1

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006338 - chromatin remodeling GO:0007062 - sister chromatid cohesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1129 Sc			1 889
+	Hs
		229407 SMCA5_HUMAN (86-1094): 0: 869: 46.69		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Hs
		658677 SMCA1_HUMAN (70-1079): 0: 869: 46.98		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Sc
		696200 ISW1_YEAST (1-1129): 0: 932: 100.00		STH1_YEAST (275-377): 2.49e-11: 69.8: 24.27
+	Sc
		744895 ISW1_YEAST (1-1129): 0: 932: 100.00		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84
+	Hs
		229311 SMCA5_HUMAN (86-1094): 0: 869: 46.69		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		631352 SMCA1_HUMAN (70-1079): 0: 869: 46.98		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		229252 SMCA5_HUMAN (86-1094): 0: 869: 46.69		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		243979 SMCA1_HUMAN (70-1079): 0: 869: 46.98		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		229448 SMCA5_HUMAN (86-1094): 0: 869: 46.69		PHIP_HUMAN (19-293): 6.82e-20: 97.9: 12.77
+	Mm
		57185 CHD7_MOUSE (25-1127): 0: 808: 26.50		SMCA4_MOUSE (9-122): 2.28e-30: 131: 30.17
+	Hs
		847103 CHD7_HUMAN (25-1127): 0: 804: 26.50		SMCA4_HUMAN (9-122): 8.4e-29: 126: 29.92
+	Sc
		603344 ISW2_YEAST (19-1108): 0: 803: 46.97		SNF2_YEAST (8-168): 6.81e-25: 114: 23.93
+	Hs
		1342808 CHD7_HUMAN (25-1127): 0: 804: 26.50		BRD7_HUMAN (2-258): 1.02e-24: 112: 12.36
+	Hs
		1199209 CHD7_HUMAN (25-1127): 0: 804: 26.50		PB1_HUMAN (234-742): 1.78e-19: 96.7: 14.64
+	Hs
		631414 CHD3_HUMAN (45-1120): 0: 770: 25.63		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		244356 CHD3_HUMAN (45-1120): 0: 770: 25.63		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		1255033 CHD5_HUMAN (45-1127): 0: 782: 25.58		PHIP_HUMAN (19-293): 6.82e-20: 97.9: 12.77
+	Sc
		969433 ISW2_YEAST (19-1108): 0: 803: 46.97		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84
+	Hs
		600135 CHD3_HUMAN (45-1120): 0: 770: 25.63		TAF1_HUMAN (3-203): 4.84e-19: 95.2: 11.82
+	Hs
		1255051 CHD5_HUMAN (45-1127): 0: 782: 25.58		ZMYD8_HUMAN (19-121): 2.55e-15: 82.8: 20.00