Protein: SLA1
Actin cytoskeleton-regulatory complex protein SLA1

Gene: SLA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 226
UniProt ID: P32790

Gene Ontology (top 5):
GO:0000147 - actin cortical patch assembly
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

744809

YSC84
Protein YSC84

9

17

Small-scale

0.975

High

744879

LSB3
LAS seventeen-binding protein 3

8

20

Small-scale

0.972

High

744808

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

5

13

Small-scale

0.935

High

587294

ABP1
Actin-binding protein

4

6

Small-scale

0.910

High

739292

ECM25
Protein ECM25

5

0

High-throughput

0.879

High

509461

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

9

Small-scale

0.873

High

744852

RV167
Reduced viability upon starvation protein 167

3

20

Small-scale

0.862

High

744853

RSP5
E3 ubiquitin-protein ligase RSP5

2

6

Small-scale

0.825

High

665795

KPC1
Protein kinase C-like 1

2

1

High-throughput

0.817

High

744844

BZZ1
Protein BZZ1

2

5

High-throughput

0.802

High

744921

MYO5
Myosin-5

2

5

High-throughput

0.793

High

744898

INN1
Ingression protein 1

2

0

Small-scale

0.774

High

744949

LAS17
Proline-rich protein LAS17

15

7

Small-scale

0.764

High

744847

END3
Actin cytoskeleton-regulatory complex protein END3

5

8

Small-scale

0.724

High

644738

CLH
Clathrin heavy chain

5

4

Small-scale

0.723

High

744927

BSP1
F-actin capping regulator BSP1

7

0

Small-scale

0.715

High

739055

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

4

11

Small-scale

0.707

High

678082

SYP1
Suppressor of yeast profilin deletion

4

2

Small-scale

0.700

High

744842

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

7

High-throughput

0.698

High

744888

INP52
Polyphosphatidylinositol phosphatase INP52

4

4

Small-scale

0.697

High

744814

SLA2
Protein SLA2

4

7

Small-scale

0.697

High

744866

PRK1
Actin-regulating kinase PRK1

3

11

Small-scale

0.683

High

744872

GTS1
Protein GTS1

4

5

Small-scale

0.677

High

744829

VRP1
Verprolin

4

13

High-throughput

0.676

High

744902

ARK1
Actin-regulating kinase 1

3

9

Small-scale

0.664

High

744856

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.663

High

744871

MGA2
Protein MGA2

1

0

High-throughput

0.663

High

744924

ENT2
Epsin-2

3

8

Small-scale

0.661

High

743164

PP12
Serine/threonine-protein phosphatase PP1-2

3

5

Small-scale

0.660

High

744839

ARPC1
Actin-related protein 2/3 complex subunit 1

3

10

Small-scale

0.658

High

744861

HUA1
Proline-rich protein HUA1

3

0

High-throughput

0.643

High

526240

HSP72
Heat shock protein SSA2

3

6

Small-scale

0.629

High

744831

AKL1
Serine/threonine-protein kinase AKL1

2

10

Small-scale

0.619

High

744824

MYO3
Myosin-3

1

6

High-throughput

0.618

High

744822

DEF1
RNA polymerase II degradation factor 1

2

3

High-throughput

0.614

High

744944

INP53
Polyphosphatidylinositol phosphatase INP53

2

4

Small-scale

0.614

High

673265

LSB5
LAS seventeen-binding protein 5

2

0

Small-scale

0.613

High

744817

EDE1
EH domain-containing and endocytosis protein 1

2

6

Small-scale

0.613

High

744848

STM1
Suppressor protein STM1

2

1

High-throughput

0.611

High

744901

APP1
Phosphatidate phosphatase APP1

2

0

High-throughput

0.609

High

430817

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

2

1

Small-scale

0.595

High

646353

RAD53
Serine/threonine-protein kinase RAD53

2

1

High-throughput

0.595

High

744952

ENT1
Epsin-1

2

5

Small-scale

0.595

High

744892

AP18B
Clathrin coat assembly protein AP180B

2

9

Small-scale

0.594

High

744947

LDB17
Protein LDB17

2

0

Small-scale

0.587

High

744836

ATG8
Autophagy-related protein 8

2

6

Small-scale

0.584

High

744816

SPO23
Sporulation protein 23

1

0

High-throughput

0.584

High

744903

MPS1
Serine/threonine-protein kinase MPS1

1

4

High-throughput

0.568

High

744916

STD1
Protein STD1

1

1

High-throughput

0.560

High

638989

VPS1
Vacuolar protein sorting-associated protein 1

1

3

Small-scale

0.552

High

544250

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.552

High

416212

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

4

High-throughput

0.541

High

598833

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.541

High

677743

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

1

High-throughput

0.541

High

697375

MIG1
Regulatory protein MIG1

1

2

High-throughput

0.541

High

733627

MGM1
Dynamin-like GTPase MGM1, mitochondrial

1

3

High-throughput

0.541

High

744818

SCD5
Protein SCD5

1

1

High-throughput

0.541

High

744830

AP2A
AP-2 complex subunit alpha

1

8

High-throughput

0.541

High

744832

ATM
Serine/threonine-protein kinase TEL1

1

3

High-throughput

0.541

High

744833

ATR
Serine/threonine-protein kinase MEC1

1

3

High-throughput

0.541

High

744838

AIM3
Altered inheritance of mitochondria protein 3

1

8

High-throughput

0.541

High

744855

IMB4
Importin subunit beta-4

1

3

High-throughput

0.541

High

744863

VTH1
VPS10 homolog 1

1

1

High-throughput

0.541

High

744864

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

High-throughput

0.541

High

744865

NDC80
Kinetochore protein NDC80

1

6

High-throughput

0.541

High

744890

MCM6
DNA replication licensing factor MCM6

1

2

High-throughput

0.541

High

744904

ZDS2
Protein ZDS2

1

5

High-throughput

0.541

High

744913

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

6

High-throughput

0.541

High

744918

NHP10
Non-histone protein 10

1

14

High-throughput

0.541

High

744931

SPO75
Sporulation-specific protein 75

1

1

High-throughput

0.541

High

744934

MDN1
Midasin

1

4

High-throughput

0.541

High

744935

TGS1
Trimethylguanosine synthase

1

1

High-throughput

0.541

High

503370

RL11A
Large ribosomal subunit protein uL5A

1

2

High-throughput

0.536

High

721793

XPO1
Exportin-1

1

5

High-throughput

0.536

High

744884

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.536

High

458547

SEC4
Ras-related protein SEC4

1

0

Small-scale

0.529

High

448157

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.518

High

448373

RAD1
DNA repair protein RAD1

1

0

High-throughput

0.518

High

560150

ATR1
Aminotriazole resistance protein

1

0

High-throughput

0.518

High

654776

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.518

High

666655

AP2
AP-1-like transcription factor YAP2

1

0

High-throughput

0.518

High

673151

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.518

High

725953

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.518

High

744815

DUR3
Urea active transporter

1

0

High-throughput

0.518

High

744819

CLG1
PHO85 cyclin CLG1

1

0

High-throughput

0.518

High

744826

MUD2
Splicing factor MUD2

1

0

High-throughput

0.518

High

744827

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.518

High

744834

TBS1
Uncharacterized transcriptional regulatory protein TBS1

1

0

High-throughput

0.518

High

744835

KTR3
Probable mannosyltransferase KTR3

1

0

High-throughput

0.518

High

744877

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.518

High

744881

SFH5
Phosphatidylinositol transfer protein SFH5

1

0

High-throughput

0.518

High

744897

CBK1
Serine/threonine-protein kinase CBK1

1

0

High-throughput

0.518

High

744900

DMA2
E3 ubiquitin-protein ligase DMA2

1

0

High-throughput

0.518

High

744905

VPS9
Vacuolar protein sorting-associated protein 9

1

0

High-throughput

0.518

High

744911

SEN1
Helicase SEN1

1

0

High-throughput

0.518

High

744920

URC2
Uracil catabolism protein 2

1

0

High-throughput

0.518

High

744922

GAL83
SNF1 protein kinase subunit beta-3

1

0

High-throughput

0.518

High

744923

YM87
Uncharacterized membrane protein YMR253C

1

0

High-throughput

0.518

High

744926

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.518

High

744932

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.518

High

744937

HUA2
Protein HUA2

1

0

High-throughput

0.518

High

744946

SCM3
Protein SCM3

1

0

High-throughput

0.518

High

744950

LDB19
Protein LDB19

1

0

High-throughput

0.518

High

744953

CSR2
Transcription factor CSR2

1

0

High-throughput

0.518

High

744954

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.518

High

383278

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

364427

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.501

High

574657

KSS1
Mitogen-activated protein kinase KSS1

1

5

High-throughput

0.501

High

656402

KC11
Casein kinase I homolog 1

1

2

High-throughput

0.501

High

656726

KC12
Casein kinase I homolog 2

1

2

High-throughput

0.501

High

666161

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

2

High-throughput

0.501

High

735472

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

4

High-throughput

0.501

High

740556

IME2
Meiosis induction protein kinase IME2/SME1

1

5

High-throughput

0.501

High

744841

RCK2
Serine/threonine-protein kinase RCK2

1

1

High-throughput

0.501

High

744845

AP18A
Clathrin coat assembly protein AP180A

1

9

Small-scale

0.501

High

744869

INP51
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51

1

4

Small-scale

0.501

High

744870

AIM21
Altered inheritance of mitochondria protein 21

1

4

High-throughput

0.501

High

744876

BNI1
Protein BNI1

1

2

High-throughput

0.501

High

744917

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

3

High-throughput

0.501

High

383106

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.494

High

677830

YCZ0
Uncharacterized protein YCR100C

1

1

High-throughput

0.494

High

744813

CSE1
Importin alpha re-exporter

1

2

High-throughput

0.494

High

744820

MTH1
Protein MTH1

1

1

High-throughput

0.494

High

744828

GMH1
Protein GMH1

1

1

High-throughput

0.494

High

744896

TDA7
Topoisomerase I damage affected protein 7

1

7

High-throughput

0.494

High

744914

MLP1
Protein MLP1

1

5

High-throughput

0.494

High

744933

FDH1
Formate dehydrogenase 1

1

1

High-throughput

0.494

High

744943

RBD2
Rhomboid-type serine protease 2

1

1

High-throughput

0.494

High

744948

YD206
Putative cation exchanger YDL206W

1

1

High-throughput

0.494

High

744928

TSR2
Pre-rRNA-processing protein TSR2

1

0

High-throughput

0.493

High

432998

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.489

High

744850

RS14B
Small ribosomal subunit protein uS11B

1

2

High-throughput

0.489

High

605294

CAP
Adenylyl cyclase-associated protein

1

0

High-throughput

0.486

High

737981

KRE6
Beta-glucan synthesis-associated protein KRE6

1

0

Small-scale

0.486

High

548188

BIK1
Nuclear fusion protein BIK1

1

1

High-throughput

0.481

High

687037

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

5

Small-scale

0.481

High

726873

HS104
Heat shock protein 104

1

4

Small-scale

0.481

High

448839

STE3
Pheromone a factor receptor

1

0

Small-scale

0.480

High

744843

GGA2
ADP-ribosylation factor-binding protein GGA2

1

0

Small-scale

0.480

High

744912

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.480

High

381978

H4
Histone H4

1

6

High-throughput

0.479

High

594276

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

674505

RS2
Small ribosomal subunit protein uS5

1

1

Small-scale

0.479

High

679510

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

706586

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

709649

BMH1
Protein BMH1

1

3

High-throughput

0.479

High

736074

ARP2
Actin-related protein 2

1

4

High-throughput

0.479

High

744812

ARPC4
Actin-related protein 2/3 complex subunit 4

1

1

High-throughput

0.479

High

744821

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

744823

BDF1
Bromodomain-containing factor 1

1

11

High-throughput

0.479

High

744825

CENPA
Histone H3-like centromeric protein CSE4

1

20

High-throughput

0.479

High

744840

KPR2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.479

High

744851

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

744868

ARPC5
Actin-related protein 2/3 complex subunit 5

1

1

High-throughput

0.479

High

744875

COPB2
Coatomer subunit beta'

1

4

Small-scale

0.479

High

744882

ARP3
Actin-related protein 3

1

4

High-throughput

0.479

High

744893

COPA
Coatomer subunit alpha

1

4

Small-scale

0.479

High

744894

ARPC2
Actin-related protein 2/3 complex subunit 2

1

1

High-throughput

0.479

High

744907

H3
Histone H3

1

20

High-throughput

0.479

High

744910

NUM1
Nuclear migration protein NUM1

1

5

High-throughput

0.479

High

744925

ARPC3
Actin-related protein 2/3 complex subunit 3

1

1

High-throughput

0.479

High

744939

PSH1
RING finger protein PSH1

1

4

High-throughput

0.479

High

744941

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

744951

CMR1
DNA damage-binding protein CMR1

1

6

High-throughput

0.479

High

744854

FIR1
Factor interacting with REF2

1

0

Small-scale

0.460

High

744889

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.460

High

744906

SLG1
Protein SLG1

1

0

Small-scale

0.460

High

744810

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

744919

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

744929

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

744945

PRR2
Serine/threonine-protein kinase PRR2

1

5

High-throughput

0.457

High

427191

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

523429

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

531662

RL4A
Large ribosomal subunit protein uL4A

1

4

High-throughput

0.445

High

569739

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.445

High

569947

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.445

High

592125

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

670503

SIS1
Protein SIS1

1

3

High-throughput

0.445

High

741234

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

744849

CAJ1
Protein CAJ1

1

4

High-throughput

0.445

High

744857

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

744885

RL4B
Large ribosomal subunit protein uL4B

1

4

High-throughput

0.445

High

744887

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.445

High

744942

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.445

High

744837

MMS4
Crossover junction endonuclease MMS4

1

0

High-throughput

0.438

High

744955

YL363
Uncharacterized protein YLR363W-A

1

0

High-throughput

0.438

High

672485

SYNM
Asparagine--tRNA ligase, mitochondrial

1

4

High-throughput

0.437

High

732117

COPG
Coatomer subunit gamma

1

8

Small-scale

0.437

High

744811

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

744874

COPB
Coatomer subunit beta

1

5

Small-scale

0.437

High

744862

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

655421

RS3A2
Small ribosomal subunit protein eS1B

1

1

High-throughput

0.407

High

689187

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.407

High

712529

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.407

High

744858

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.407

High

560276

KEX2
Kexin

2

0

Small-scale

0.334

High

744938

PER33
Pore and endoplasmic reticulum protein of 33 kDa

2

0

High-throughput

0.329

High

571814

SNA3
Protein SNA3

2

0

High-throughput

0.317

High

554323

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

0

High-throughput

0.282

High

673625

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.282

High

677096

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.282

High

735897

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.282

High

744846

GAA1
GPI transamidase component GAA1

1

0

High-throughput

0.282

High

744859

LDO45
Lipid droplet organization protein LDO45

1

0

High-throughput

0.282

High

744860

TGL3
Triacylglycerol lipase 3

1

0

High-throughput

0.282

High

744867

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.282

High

744873

SYS1
Protein SYS1

1

0

High-throughput

0.282

High

744878

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.282

High

744883

YJ85
Uncharacterized protein YJR115W

1

0

High-throughput

0.282

High

744886

ALG10
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

0

High-throughput

0.282

High

744891

VPS73
Vacuolar protein sorting-associated protein 73

1

0

High-throughput

0.282

High

744899

YNO4
Uncharacterized protein YNL144C

1

0

High-throughput

0.282

High

744915

SMA1
Spore membrane assembly protein 1

1

0

High-throughput

0.282

High

744930

ACK1
Activator of C kinase protein 1

1

0

High-throughput

0.282

High

744936

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.282

High

744940

NDOR1
NADPH-dependent diflavin oxidoreductase 1

1

0

High-throughput

0.282

High

744956

TAR1
Protein TAR1

1

0

High-throughput

0.251

Low

513840

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.249

Low

514253

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

515066

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

515234

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.249

Low

744880

COPD
Coatomer subunit delta

1

0

Small-scale

0.249

Low

744895

YN25
Putative uncharacterized protein YNL285W

1

0

High-throughput

0.238

Low

744908

YD413
Putative uncharacterized protein YDR413C

1

0

High-throughput

0.238

Low

744909

YD271
Putative uncharacterized protein YDR271C

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025