HitPredict

Interactor 1: YPT10 (P38146)
GTP-binding protein YPT10
Gene: YPT10

Interactor 2: GDI1 (P39958)
Rab GDP-dissociation inhibitor (Rab GDI) (Secretory pathway GDP dissociation inhibitor)
Gene: GDI1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.945

Property	Details
Experiments	11805837, 37968396, 11785952, 18467557, 22157956, 10394895
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 199 Sc			1 451
+	Sc
		350882 YPT1_YEAST (2-199): 6.1e-78: 233: 26.57		GDI1_YEAST (1-451): 0: 667: 100.00
+	Mm
		838709 RAB1A_MOUSE (2-198): 1.26e-80: 240: 27.59		GDIA_MOUSE (6-450): 0: 653: 54.04
+	Hs
		678344 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838625 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Hs
		678394 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		678330 RAB5C_HUMAN (4-198): 6.49e-79: 236: 36.50		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838683 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Hs
		838605 RAB5C_HUMAN (4-198): 6.49e-79: 236: 36.50		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Hs
		592123 RAB5A_HUMAN (4-198): 3.94e-78: 234: 35.00		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		592161 RAB5A_HUMAN (4-198): 3.94e-78: 234: 35.00		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Sc
		699422 YPT10_YEAST (1-199): 1.14e-94: 275: 100.00		RAEP_YEAST (5-385): 5.77e-114: 348: 25.30
+	Sc
		350859 YPT1_YEAST (2-199): 6.1e-78: 233: 26.57		RAEP_YEAST (5-385): 5.77e-114: 348: 25.30
+	Hs
		622577 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642723 RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		622619 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642743 RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		622565 RAB5C_HUMAN (4-198): 6.49e-79: 236: 36.50		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642710 RAB5C_HUMAN (4-198): 6.49e-79: 236: 36.50		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		592103 RAB5A_HUMAN (4-198): 3.94e-78: 234: 35.00		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		592106 RAB5A_HUMAN (4-198): 3.94e-78: 234: 35.00		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71