HitPredict

Interactor 1: AP3M (P38153)
AP-3 complex subunit mu (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu) (Mu-adaptin 3A) (Mu3-adaptin)
Gene: APM3

Interactor 2: AP3S (P47064)
AP-3 complex subunit sigma (AP-3 complex sigma3A subunit) (Adaptor-related protein complex 3 subunit sigma) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-adaptin 3A) (Sigma3-adaptin)
Gene: APS3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	9250663, 37968396
Identification Methods	molecular sieving, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adap_comp_sub~Clat_adaptor_s
Common GO terms	GO:0005794 - Golgi apparatus GO:0006623 - protein targeting to vacuole GO:0006886 - intracellular protein transport GO:0006896 - Golgi to vacuole transport GO:0030123 - AP-3 adaptor complex and 1 others more... GO:0030659 - cytoplasmic vesicle membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 483 Sc			1 194
+	Hs
		880428 AP1M1_HUMAN (2-482): 4.31e-148: 431: 18.42		AP1S2_HUMAN (2-175): 2.9e-65: 199: 28.16
+	Hs
		903697 AP1M2_HUMAN (2-482): 4.28e-142: 416: 18.62		AP1S1_HUMAN (1-176): 4.82e-66: 201: 27.27
+	Hs
		1299170 AP1M1_HUMAN (2-482): 4.31e-148: 431: 18.42		AP1S3_HUMAN (1-161): 2.07e-59: 184: 27.95
+	Hs
		880436 AP1M2_HUMAN (2-482): 4.28e-142: 416: 18.62		AP1S2_HUMAN (2-175): 2.9e-65: 199: 28.16
+	Hs
		903691 AP2M1_HUMAN (1-482): 1.19e-136: 402: 17.66		AP1S1_HUMAN (1-176): 4.82e-66: 201: 27.27
+	Hs
		880423 AP2M1_HUMAN (1-482): 1.19e-136: 402: 17.66		AP1S2_HUMAN (2-175): 2.9e-65: 199: 28.16
+	Hs
		1299174 AP1M2_HUMAN (2-482): 4.28e-142: 416: 18.62		AP1S3_HUMAN (1-161): 2.07e-59: 184: 27.95
+	Hs
		1287472 AP2M1_HUMAN (1-482): 1.19e-136: 402: 17.66		AP1S3_HUMAN (1-161): 2.07e-59: 184: 27.95
+	Hs
		864097 AP2M1_HUMAN (1-482): 1.19e-136: 402: 17.66		AP2S1_HUMAN (1-160): 1.58e-57: 179: 29.38
+	Mm
		915560 AP2M1_MOUSE (1-482): 1.19e-136: 402: 17.66		AP2S1_MOUSE (1-160): 1.58e-57: 179: 29.38
+	Hs
		1267501 AP3M1_HUMAN (1-482): 7.43e-124: 369: 18.31		AP3S1_HUMAN (1-164): 6.8e-68: 207: 44.51
+	Dm
		248304 O62530_DROME (1-482): 8.24e-132: 390: 17.13		Q9VDC3_DROME (1-160): 2.84e-58: 181: 29.38
+	Hs
		887150 AP3M1_HUMAN (1-482): 7.43e-124: 369: 18.31		AP3S2_HUMAN (1-163): 5.73e-66: 202: 42.95
+	At
		187811 AP2M_ARATH (2-482): 3.28e-133: 393: 15.37		AP2S_ARATH (1-160): 4.82e-56: 175: 30.63
+	Hs
		864052 AP3M2_HUMAN (1-482): 4.35e-113: 341: 18.31		AP3S1_HUMAN (1-164): 6.8e-68: 207: 44.51
+	Hs
		864041 AP3M2_HUMAN (1-482): 4.35e-113: 341: 18.31		AP3S2_HUMAN (1-163): 5.73e-66: 202: 42.95
+	Sc
		715577 AP1M1_YEAST (1-483): 1.03e-122: 368: 16.73		AP1S1_YEAST (2-167): 5.8e-49: 157: 22.62
+	Sc
		959833 AP2M_YEAST (1-483): 1.21e-120: 363: 13.59		AP2S_YEAST (2-160): 1.88e-50: 161: 28.57
+	Hs
		119741 AP4M1_HUMAN (1-483): 1.93e-108: 331: 14.03		AP4S1_HUMAN (1-162): 1.79e-51: 164: 37.04
+	Hs
		864094 STON2_HUMAN (125-483): 3.57e-86: 285: 12.59		AP2S1_HUMAN (1-160): 1.58e-57: 179: 29.38