HitPredict

Interactor 1: IMB2 (P38217)
Importin subunit beta-2 (Importin-104) (Karyopherin subunit beta-2) (Karyopherin-104) (Transportin) (TRN)
Gene: KAP104

Interactor 2: NU145 (P49687)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	8849456, 9368759
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 918 Sc			1 1317
+	Sc
		746533 IMB2_YEAST (1-918): 0: 580: 100.00		NU100_YEAST (45-542): 1.84e-14: 80.8: 14.10
+	Sc
		746518 IMB2_YEAST (1-918): 0: 580: 100.00		NUP57_YEAST (118-368): 1.26e-10: 67.7: 15.33
+	Sc
		746534 IMB2_YEAST (1-918): 0: 580: 100.00		NU116_YEAST (43-484): 6.18e-10: 66.2: 12.29
+	Sc
		746532 IMB2_YEAST (1-918): 0: 580: 100.00		NUP49_YEAST (3-140): 3.57e-10: 66.1: 29.68
+	Sc
		746519 IMB2_YEAST (1-918): 0: 580: 100.00		NUP42_YEAST (2-285): 1.65e-09: 63.8: 17.86
+	Hs
		858024 TNPO1_HUMAN (1-864): 7.94e-177: 537: 33.03		NUP98_HUMAN (1-435): 2.24e-14: 80.9: 13.29
+	Hs
		834652 TNPO1_HUMAN (1-864): 7.94e-177: 537: 33.03		NU153_HUMAN (16-447): 4.54e-11: 70: 10.50
+	Hs
		727300 TNPO1_HUMAN (1-864): 7.94e-177: 537: 33.03		NU214_HUMAN (14-341): 6.71e-11: 69.6: 16.43
+	Hs
		155553 TNPO2_HUMAN (3-862): 2.26e-166: 510: 31.89		NUP98_HUMAN (1-435): 2.24e-14: 80.9: 13.29
+	Xl
		1137359 Q5U4V0_XENLA (1-862): 5.22e-172: 524: 32.76		NU153_XENLA (3-435): 2.2e-09: 64.6: 14.07
+	Hs
		155550 TNPO2_HUMAN (3-862): 2.26e-166: 510: 31.89		NU153_HUMAN (16-447): 4.54e-11: 70: 10.50
+	Ce
		248185 O62332_CAEEL (3-863): 1.11e-155: 481: 29.85		Q9U3B9_CAEEL (104-343): 6.47e-18: 91.6: 21.81
+	Ce
		248186 O62332_CAEEL (3-863): 1.11e-155: 481: 29.85		Q9XWK3_CAEEL (4-179): 3.66e-12: 72.6: 28.89
+	Ce
		248166 O62332_CAEEL (3-863): 1.11e-155: 481: 29.85		P91457_CAEEL (3-458): 2.3e-09: 64.3: 14.83
+	Tt
		101907 G0SGZ5_CHATD (3-862): 2.36e-138: 438: 28.24		NU145_CHATD (7-472): 2.07e-10: 67.8: 12.30
+	Hs
		857978 IMB1_HUMAN (13-885): 1.66e-97: 327: 11.77		NUP98_HUMAN (1-435): 2.24e-14: 80.9: 13.29
+	Xl
		853819 IMB_XENLA (13-885): 1.77e-96: 324: 11.44		Q5EWX9_XENLA (1-330): 2.1e-13: 77.3: 16.09
+	At
		1321465 IMB1_ARATH (11-888): 1.66e-97: 327: 12.86		NUP1_ARATH (3-332): 1.74e-11: 71.2: 16.15
+	Hs
		834599 IMB1_HUMAN (13-885): 1.66e-97: 327: 11.77		NU153_HUMAN (16-447): 4.54e-11: 70: 10.50
+	Hs
		727254 IMB1_HUMAN (13-885): 1.66e-97: 327: 11.77		NU214_HUMAN (14-341): 6.71e-11: 69.6: 16.43