HitPredict

Interactor 1: RFC5 (P38251)
Replication factor C subunit 5 (Replication factor C5) (Activator 1 40 kDa subunit)
Gene: RFC5

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	16554755, 22199229
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 354 Sc			1 136
+	Hs
		721964 RFC4_HUMAN (2-353): 5.88e-103: 309: 29.26		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		721966 RFC4_HUMAN (2-353): 5.88e-103: 309: 29.26		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		777968 RFC3_HUMAN (1-351): 1.57e-101: 305: 43.88		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		722090 RFC2_HUMAN (3-352): 1.34e-92: 282: 24.29		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		722091 RFC2_HUMAN (3-352): 1.34e-92: 282: 24.29		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Sc
		772431 RFC2_YEAST (2-351): 3.23e-97: 293: 25.63		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Hs
		777841 RFC5_HUMAN (3-354): 7.94e-90: 274: 23.51		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		777842 RFC5_HUMAN (3-354): 7.94e-90: 274: 23.51		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Sc
		751282 RFC3_YEAST (3-354): 1.08e-86: 266: 22.25		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		772262 RFC4_YEAST (3-349): 8.42e-84: 258: 22.19		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Hs
		722079 RFC2_HUMAN (3-352): 1.34e-92: 282: 24.29		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		777827 RFC5_HUMAN (3-354): 7.94e-90: 274: 23.51		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Sc
		730788 RFC3_YEAST (3-354): 1.08e-86: 266: 22.25		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04