HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	22689573, 20016594, 20016603
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 95
+	Hs
		749351 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36
+	Hs
		928187 TRIM5_HUMAN (10-339): 1.37e-63: 227: 13.27		SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36
+	Hs
		902556 TRI26_HUMAN (12-287): 2.53e-51: 193: 14.53		SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00