HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: GCC1 (Q96CN9)
GRIP and coiled-coil domain-containing protein 1 (Golgi coiled-coil protein 1)
Gene: GCC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	25184681
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 775
+	Hs
		749622 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH14_HUMAN (2-659): 3.29e-23: 108: 13.02
+	Hs
		724691 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH9_HUMAN (323-771): 2.4e-16: 86.3: 8.91
+	Hs
		148473 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		CTRO_HUMAN (156-700): 4.64e-13: 75.3: 17.66
+	Hs
		551628 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		DESP_HUMAN (131-704): 1.24e-11: 70.7: 17.71
+	Hs
		749516 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		PLEC_HUMAN (150-708): 1.82e-10: 67.2: 17.67
+	Hs
		725099 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH10_HUMAN (2-326): 5.6e-09: 62: 8.54
+	Hs
		522639 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH7_HUMAN (142-773): 4.14e-26: 117: 11.80
+	Hs
		584968 RO52_HUMAN (15-390): 2.55e-68: 241: 12.86		PLEC_HUMAN (150-708): 1.82e-10: 67.2: 17.67
+	Hs
		528393 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH6_HUMAN (1-389): 1.91e-11: 70.1: 10.94
+	Hs
		149258 TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52		CTRO_HUMAN (156-700): 4.64e-13: 75.3: 17.66
+	Hs
		1189797 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH14_HUMAN (2-659): 3.29e-23: 108: 13.02
+	Hs
		725005 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH9_HUMAN (323-771): 2.4e-16: 86.3: 8.91
+	Hs
		725238 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH10_HUMAN (2-326): 5.6e-09: 62: 8.54
+	Mm
		1093546 TRI72_MOUSE (18-91): 9.41e-12: 71.5: 30.26		MYH9_MOUSE (449-774): 2.04e-13: 76.6: 8.28