HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26831064
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 449
+	Hs
		749360 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		428062 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		749361 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		1309481 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		1175047 TRI58_HUMAN (16-390): 3.39e-69: 243: 12.53		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		537100 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		TBA8_HUMAN (1-439): 0: 698: 90.66
+	Hs
		585085 RO52_HUMAN (15-390): 2.55e-68: 241: 12.86		TBA8_HUMAN (1-439): 0: 698: 90.66
+	Hs
		1318713 TRIM5_HUMAN (10-339): 1.37e-63: 227: 13.27		TBA8_HUMAN (1-439): 0: 698: 90.66
+	Hs
		1309480 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		933342 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		428414 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		1313665 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		933960 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		TBB4B_HUMAN (1-437): 0: 697: 40.73