HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: ASH2L (Q9UBL3)
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)
Gene: ASH2L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.586

The method score is based on:

Property Details
Experiments 26831064, 22990118
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1863
Hs

1 628
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024