Interactor 1: MED31 (P38633)
Mediator of RNA polymerase II transcription subunit 31 (Hpr1 suppressor protein 1) (Mediator complex subunit 31)
Gene: SOH1

Interactor 2: MED7 (Q08278)
Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7)
Gene: MED7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 11283351, 16554755, 37968396, 26317468, 28575439, 19057509, 33933450, 20123732, 16429126
Identification Methods two hybrid pooling approach, affinity chromatography technology, two hybrid, x-ray crystallography, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med31~Med7
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 3 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 127
Sc

1 222
+ Hs
+ At
+ Dm
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024