HitPredict

Interactor 1: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31722399
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0016887 - ATP hydrolysis activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 679 Hs			1 1493
+	Hs
		501998 BIP_HUMAN (53-677): 0: 566: 50.55		ERCC6_HUMAN (1-1493): 0: 1168: 100.00
+	Hs
		871693 HSP72_HUMAN (50-653): 0: 868: 49.11		CHD5_HUMAN (300-1446): 0: 783: 19.15
+	Hs
		504094 HSP7C_HUMAN (51-653): 0: 883: 50.16		CHD4_HUMAN (303-1439): 0: 766: 18.35
+	Hs
		713973 HS71L_HUMAN (49-673): 0: 883: 47.59		CHD4_HUMAN (303-1439): 0: 766: 18.35
+	Hs
		503984 HSP7C_HUMAN (51-653): 0: 883: 50.16		CHD3_HUMAN (303-1446): 0: 759: 19.68
+	Hs
		751630 GRP75_HUMAN (1-679): 0: 873: 100.00		CHD4_HUMAN (303-1439): 0: 766: 18.35
+	Hs
		751600 GRP75_HUMAN (1-679): 0: 873: 100.00		CHD3_HUMAN (303-1446): 0: 759: 19.68
+	Hs
		229290 HSP7C_HUMAN (51-653): 0: 883: 50.16		SMCA5_HUMAN (368-1383): 0: 698: 20.75
+	Hs
		503711 HSP7C_HUMAN (51-653): 0: 883: 50.16		SMCA2_HUMAN (228-1247): 0: 660: 19.72
+	Dm
		505047 HSP7D_DROME (51-653): 0: 866: 50.97		BRM_DROME (228-1361): 0: 662: 18.59
+	Sc
		697397 HSP7E_YEAST (29-653): 0: 766: 63.43		CHD1_YEAST (409-1426): 0: 748: 20.90
+	Sc
		478583 HSP77_YEAST (37-653): 0: 785: 66.61		ISW2_YEAST (351-1234): 0: 643: 23.85
+	Sc
		766255 HSP7E_YEAST (29-653): 0: 766: 63.43		ISW2_YEAST (351-1234): 0: 643: 23.85
+	Hs
		501847 BIP_HUMAN (53-677): 0: 566: 50.55		SMCA2_HUMAN (228-1247): 0: 660: 19.72
+	Hs
		871587 HSP72_HUMAN (50-653): 0: 868: 49.11		ERC6L_HUMAN (482-1007): 6.57e-91: 324: 35.92
+	Sc
		687698 HSP7E_YEAST (29-653): 0: 766: 63.43		BTAF1_YEAST (497-1017): 9.72e-81: 296: 35.56
+	Sc
		744871 HSP7E_YEAST (29-653): 0: 766: 63.43		ISW1_YEAST (463-988): 1.06e-75: 277: 36.60
+	Sc
		696211 HSP7E_YEAST (29-653): 0: 766: 63.43		STH1_YEAST (507-991): 1.19e-71: 266: 33.60
+	Sc
		478251 HSP77_YEAST (37-653): 0: 785: 66.61		RAD26_YEAST (1190-1456): 1.02e-40: 166: 21.17
+	Sc
		766034 HSP7E_YEAST (29-653): 0: 766: 63.43		RAD26_YEAST (1190-1456): 1.02e-40: 166: 21.17