HitPredict

Interactor 1: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: MT21A (Q8WXB1)
Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A)
Gene: METTL21A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23349634
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031072 - heat shock protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 679 Hs			1 218
+	Hs
		504476 HSP7C_HUMAN (51-653): 0: 883: 50.16		MT21A_HUMAN (1-218): 2.1e-77: 233: 100.00
+	Hs
		714031 HS71L_HUMAN (49-673): 0: 883: 47.59		MT21A_HUMAN (1-218): 2.1e-77: 233: 100.00
+	Hs
		483797 HS71B_HUMAN (51-652): 0: 873: 49.27		MT21A_HUMAN (1-218): 2.1e-77: 233: 100.00
+	Hs
		871699 HSP72_HUMAN (50-653): 0: 868: 49.11		MT21A_HUMAN (1-218): 2.1e-77: 233: 100.00
+	Hs
		504537 HSP7C_HUMAN (51-653): 0: 883: 50.16		EFMT3_HUMAN (13-216): 3.92e-64: 200: 42.51
+	Hs
		714042 HS71L_HUMAN (49-673): 0: 883: 47.59		EFMT3_HUMAN (13-216): 3.92e-64: 200: 42.51
+	Hs
		871718 HSP72_HUMAN (50-653): 0: 868: 49.11		EFMT3_HUMAN (13-216): 3.92e-64: 200: 42.51
+	Hs
		504229 HSP7C_HUMAN (51-653): 0: 883: 50.16		MT21C_HUMAN (21-212): 2.38e-55: 179: 31.98
+	Hs
		713993 HS71L_HUMAN (49-673): 0: 883: 47.59		MT21C_HUMAN (21-212): 2.38e-55: 179: 31.98
+	Mm
		751934 GRP75_MOUSE (1-679): 0: 861: 98.38		MT21E_MOUSE (19-215): 1.24e-61: 194: 36.63
+	Hs
		504315 HSP7C_HUMAN (51-653): 0: 883: 50.16		CMKMT_HUMAN (32-218): 1.04e-47: 160: 19.07
+	Hs
		751832 GRP75_HUMAN (1-679): 0: 873: 100.00		MT21D_HUMAN (28-215): 6.6e-46: 153: 34.15
+	Hs
		504677 HSP7C_HUMAN (51-653): 0: 883: 50.16		MET22_HUMAN (7-200): 7.21e-40: 142: 21.36
+	Hs
		714062 HS71L_HUMAN (49-673): 0: 883: 47.59		MET22_HUMAN (7-200): 7.21e-40: 142: 21.36
+	Hs
		504646 HSP7C_HUMAN (51-653): 0: 883: 50.16		ANM1_HUMAN (57-208): 1.75e-33: 125: 16.03
+	Hs
		751797 GRP75_HUMAN (1-679): 0: 873: 100.00		ANM1_HUMAN (57-208): 1.75e-33: 125: 16.03
+	Hs
		751848 GRP75_HUMAN (1-679): 0: 873: 100.00		ANM8_HUMAN (57-170): 6.51e-32: 121: 15.25
+	Hs
		504370 HSP7C_HUMAN (51-653): 0: 883: 50.16		ETKMT_HUMAN (44-176): 3.41e-28: 108: 22.96
+	Hs
		871737 HSP72_HUMAN (50-653): 0: 868: 49.11		ANM6_HUMAN (57-197): 2e-32: 122: 16.03
+	Hs
		316472 BIP_HUMAN (53-677): 0: 566: 50.55		MET18_HUMAN (8-189): 1.88e-33: 125: 19.72