HitPredict

Interactor 1: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 679 Hs			1 779
+	Hs
		504760 HSP7C_HUMAN (51-653): 0: 883: 50.16		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		871786 HSP72_HUMAN (50-653): 0: 868: 49.11		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		504247 HSP7C_HUMAN (51-653): 0: 883: 50.16		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		751684 GRP75_HUMAN (1-679): 0: 873: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		503422 HSP7C_HUMAN (51-653): 0: 883: 50.16		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		504908 HSP7C_HUMAN (51-653): 0: 883: 50.16		SWP70_HUMAN (55-446): 3.06e-44: 170: 11.36
+	Hs
		596368 GRP75_HUMAN (1-679): 0: 873: 100.00		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		502562 BIP_HUMAN (53-677): 0: 566: 50.55		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		504388 HSP7C_HUMAN (51-653): 0: 883: 50.16		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Sc
		478627 HSP77_YEAST (37-653): 0: 785: 66.61		OSH2_YEAST (2-703): 2.25e-55: 208: 10.89
+	Hs
		751721 GRP75_HUMAN (1-679): 0: 873: 100.00		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Sc
		766288 HSP7E_YEAST (29-653): 0: 766: 63.43		OSH2_YEAST (2-703): 2.25e-55: 208: 10.89
+	Sc
		728871 HSP7E_YEAST (29-653): 0: 766: 63.43		OSH1_YEAST (2-550): 5.4e-39: 158: 10.80
+	Hs
		502214 BIP_HUMAN (53-677): 0: 566: 50.55		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		502244 BIP_HUMAN (53-677): 0: 566: 50.55		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		502209 BIP_HUMAN (53-677): 0: 566: 50.55		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Dm
		669812 BIP_DROME (53-641): 0: 566: 53.25		Q7KNQ9_DROME (5-282): 1.28e-40: 163: 19.74
+	Hs
		502315 BIP_HUMAN (53-677): 0: 566: 50.55		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93