HitPredict

Interactor 1: DBP8 (P38719)
ATP-dependent RNA helicase DBP8 (EC 3.6.4.13) (DEAD box protein 8)
Gene: DBP8

Interactor 2: UTP4 (Q06679)
U3 small nucleolar RNA-associated protein 4 (U3 snoRNA-associated protein 4) (U three protein 4) (U3 protein 4 required for transcription) (t-UTP4)
Gene: UTP4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome and 1 others more... GO:0032040 - small-subunit processome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 431 Sc			1 776
+	Sc
		635572 DBP8_YEAST (1-431): 3.8e-127: 376: 100.00		PWP2_YEAST (244-720): 2.31e-37: 152: 6.64
+	Sc
		415901 DED1_YEAST (1-400): 2.09e-123: 372: 28.78		PWP2_YEAST (244-720): 2.31e-37: 152: 6.64
+	Hs
		181727 DDX3Y_HUMAN (1-391): 1.8e-141: 420: 29.93		UTP4_HUMAN (410-699): 2.84e-20: 98: 8.48
+	Hs
		181721 DDX3Y_HUMAN (1-391): 1.8e-141: 420: 29.93		POC1A_HUMAN (504-755): 5.79e-17: 85.7: 7.35
+	Hs
		903410 DDX17_HUMAN (1-388): 3.77e-117: 360: 30.96		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		571382 DDX5_HUMAN (1-431): 3.93e-117: 356: 27.00		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		921718 DDX47_HUMAN (2-426): 4.96e-115: 346: 40.71		GBB2_HUMAN (271-595): 3.16e-22: 100: 13.98
+	Hs
		133956 DDX3X_HUMAN (1-391): 2.51e-114: 350: 30.41		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		903507 DDX47_HUMAN (2-426): 4.96e-115: 346: 40.71		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		1271621 DDX17_HUMAN (1-388): 3.77e-117: 360: 30.96		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Hs
		1271679 DDX17_HUMAN (1-388): 3.77e-117: 360: 30.96		NLE1_HUMAN (557-661): 1.4e-11: 69.5: 10.28
+	Hs
		571547 DDX5_HUMAN (1-431): 3.93e-117: 356: 27.00		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27
+	Sc
		630853 DRS1_YEAST (3-379): 5.26e-61: 213: 36.34		NLE1_YEAST (516-647): 4.72e-13: 74.3: 12.03
+	Hs
		757532 IF4A3_HUMAN (4-379): 1.09e-55: 191: 32.11		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		757710 IF4A3_HUMAN (4-379): 1.09e-55: 191: 32.11		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27