HitPredict

Interactor 1: COS8 (P38723)
Protein COS8
Gene: COS8

Interactor 2: MST28 (P39552)
Multicopy suppressor of SEC21 protein 28 (DUP240 protein MST28)
Gene: MST28

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	16093310
Identification Methods	ubiquitin reconstruction, protein complementation assay
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 381 Sc			1 234
+	Sc
		859928 COS6_YEAST (1-380): 0: 523: 81.05		MST27_YEAST (1-234): 8.57e-98: 286: 96.58
+	Sc
		753276 COS8_YEAST (1-381): 0: 520: 100.00		MST27_YEAST (1-234): 8.57e-98: 286: 96.58
+	Sc
		90166 COS8_YEAST (1-381): 0: 520: 100.00		YAJ3_YEAST (53-226): 7.7e-59: 185: 34.29
+	Sc
		861656 COS1_YEAST (1-380): 0: 540: 77.90		COS6_YEAST (11-175): 2.27e-32: 122: 19.16
+	Sc
		762855 MST28_YEAST (16-176): 1.01e-49: 169: 19.28		MST28_YEAST (1-234): 4.11e-104: 302: 100.00
+	Sc
		762860 MST28_YEAST (16-176): 1.01e-49: 169: 19.28		MST27_YEAST (1-234): 8.57e-98: 286: 96.58
+	Sc
		859926 MST27_YEAST (16-176): 4.18e-45: 156: 18.68		MST27_YEAST (1-234): 8.57e-98: 286: 96.58
+	Sc
		762852 PRM8_YEAST (16-186): 3.16e-56: 186: 21.26		PRM9_YEAST (1-227): 2.4e-82: 249: 51.92
+	Sc
		762804 UIP3_YEAST (16-221): 1.35e-48: 166: 19.52		UIP3_YEAST (1-227): 2.57e-83: 249: 47.68
+	Sc
		762805 UIP3_YEAST (16-221): 1.35e-48: 166: 19.52		KTD1_YEAST (1-227): 8e-80: 240: 42.31
+	Sc
		762842 KTD1_YEAST (16-161): 1.73e-43: 152: 20.95		KTD1_YEAST (1-227): 8e-80: 240: 42.31
+	Sc
		629917 YCP7_YEAST (22-189): 6.11e-43: 151: 23.86		YCP7_YEAST (5-227): 7.13e-75: 228: 37.83
+	Sc
		753292 YHE4_YEAST (21-199): 4.25e-26: 106: 16.67		YHE4_YEAST (23-226): 4.3e-40: 139: 22.38