Protein: MFT1
THO complex subunit MFT1 (Mitochondrial fusion target protein 1)

Gene: MFT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 105
UniProt ID: P33441

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000347 - THO complex
GO:0000445 - THO complex part of transcription export complex
GO:0000446 - nucleoplasmic THO complex
GO:0000781 - chromosome, telomeric region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

605884

HPR1
THO complex subunit HPR1

15

0

Small-scale

0.934

High

753256

THO2
THO complex subunit 2

10

0

Small-scale

0.926

High

150159

THP2
THO complex subunit THP2

10

0

Small-scale

0.923

High

753272

YRA1
RNA annealing protein YRA1

5

1

Small-scale

0.716

High

676712

GBP2
Serine/arginine

5

2

Small-scale

0.712

High

753267

SUB2
ATP-dependent RNA helicase SUB2

7

0

Small-scale

0.711

High

753258

TEX1
Protein TEX1

6

0

Small-scale

0.699

High

753236

HRB1
Serine/arginine

5

1

Small-scale

0.650

High

753228

MFT1
THO complex subunit MFT1

3

0

Small-scale

0.622

High

753271

NCBP2
Nuclear cap-binding protein subunit 2

2

0

Small-scale

0.559

High

526303

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.549

High

544337

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.549

High

753244

DLS1
Protein DLS1

1

0

High-throughput

0.493

High

366990

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.489

High

523505

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.489

High

740133

RPN2
26S proteasome regulatory subunit RPN2

1

1

High-throughput

0.489

High

753265

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

438134

NOT2
General negative regulator of transcription subunit 2

1

0

Small-scale

0.458

High

594292

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.458

High

753229

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

Small-scale

0.458

High

753245

MLP2
Protein MLP2

1

0

High-throughput

0.458

High

753275

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

753276

MEX67
mRNA export factor MEX67

1

0

High-throughput

0.458

High

602389

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.457

High

673694

KCC4
Probable serine/threonine-protein kinase KCC4

1

1

High-throughput

0.457

High

753233

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.457

High

753263

PKH3
Serine/threonine-protein kinase PKH3

1

1

High-throughput

0.457

High

364449

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.439

High

590188

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

1

High-throughput

0.437

High

664588

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

1

High-throughput

0.437

High

592147

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

603442

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.407

High

741276

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

753235

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.407

High

753242

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

753243

JEM1
DnaJ-like chaperone JEM1

1

1

High-throughput

0.407

High

753250

DPH4
Diphthamide biosynthesis protein 4

1

1

High-throughput

0.407

High

753251

HLJ1
Protein HLJ1

1

1

High-throughput

0.407

High

753260

ACAC
Acetyl-CoA carboxylase

1

1

High-throughput

0.407

High

383610

RS17A
Small ribosomal subunit protein eS17A

2

0

High-throughput

0.298

High

434972

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.298

High

448949

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.279

Low

753231

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.279

Low

753232

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.279

Low

753253

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.279

Low

753262

IMA1
Importin subunit alpha

1

0

High-throughput

0.279

Low

753249

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

0

High-throughput

0.269

Low

753268

ULS1
ATP-dependent helicase ULS1

1

0

High-throughput

0.269

Low

448688

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.261

Low

656412

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.261

Low

692319

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

745269

ELM1
Serine/threonine-protein kinase ELM1

1

0

High-throughput

0.261

Low

753255

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

753269

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.261

Low

753247

BUD27
Bud site selection protein 27

1

0

Small-scale

0.251

Low

753264

GIS1
Transcriptional activator/repressor GIS1

1

0

Small-scale

0.251

Low

149676

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

410035

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433550

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

438281

NOT3
General negative regulator of transcription subunit 3

1

0

Small-scale

0.249

Low

441816

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

454970

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

502950

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504133

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

512049

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

512353

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

512918

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

577009

CBP7
Cytochrome B translational activator CBS2

1

0

High-throughput

0.249

Low

689360

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

706666

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

738804

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.249

Low

753230

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

753234

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

753239

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

753240

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

0

Small-scale

0.249

Low

753254

HFM1
ATP-dependent DNA helicase MER3

1

0

Small-scale

0.249

Low

753257

CAF40
Protein CAF40

1

0

Small-scale

0.249

Low

753259

YNO0
Uncharacterized protein YNL140C

1

0

High-throughput

0.249

Low

753261

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

753266

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

753270

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

358174

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

386656

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

403434

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.232

Low

427206

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

435875

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.232

Low

453520

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

531293

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.232

Low

553971

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.232

Low

575421

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

597097

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.232

Low

675867

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.232

Low

684673

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

688855

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.232

Low

712536

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.232

Low

752073

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

753237

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

753238

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

753241

IMB4
Importin subunit beta-4

1

0

High-throughput

0.232

Low

753246

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

753248

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

753252

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.232

Low

753273

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low

753274

PAA1
Polyamine N-acetyltransferase 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025