HitPredict

Interactor 1: HSE1 (P38753)
Class E vacuolar protein-sorting machinery protein HSE1
Gene: HSE1

Interactor 2: END3 (P39013)
Actin cytoskeleton-regulatory complex protein END3 (Endocytosis protein 3)
Gene: END3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	22875988
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010008 - endosome membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 452 Sc			1 349
+	Hs
		277020 STAM2_HUMAN (3-450): 4.75e-90: 285: 19.79		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		1356199 GGA1_HUMAN (7-452): 3.64e-53: 190: 15.47		SYNRG_HUMAN (12-276): 1.65e-37: 145: 15.44
+	Hs
		159921 HGS_HUMAN (1-426): 1.38e-52: 190: 13.02		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		1348862 GGA3_HUMAN (7-319): 5.97e-45: 168: 14.80		SYNRG_HUMAN (12-276): 1.65e-37: 145: 15.44
+	Ce
		136444 STAM1_CAEEL (2-435): 6.06e-66: 220: 20.87		Q9U2T9_CAEEL (3-349): 2.24e-16: 82.3: 11.75
+	Hs
		924713 GRB2_HUMAN (174-274): 1.87e-31: 121: 31.68		REPS2_HUMAN (3-348): 2.13e-47: 171: 16.89
+	Hs
		1356191 GGA2_HUMAN (5-235): 4.37e-37: 145: 16.46		SYNRG_HUMAN (12-276): 1.65e-37: 145: 15.44
+	Hs
		787889 GRB2_HUMAN (174-274): 1.87e-31: 121: 31.68		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		924919 GRB2_HUMAN (174-274): 1.87e-31: 121: 31.68		EP15R_HUMAN (12-274): 5.5e-32: 128: 17.60
+	Hs
		1078872 ITSN1_HUMAN (116-297): 4.35e-10: 64.4: 20.00		REPS2_HUMAN (3-348): 2.13e-47: 171: 16.89
+	Ce
		1089160 Q17796_CAEEL (5-242): 1.27e-37: 147: 15.77		Q9U2T9_CAEEL (3-349): 2.24e-16: 82.3: 11.75
+	Hs
		61732 A6H8W8_HUMAN (196-273): 2.46e-11: 68.4: 30.86		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		787985 ITSN2_HUMAN (196-273): 2.11e-11: 68.4: 30.86		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		787920 ITSN1_HUMAN (116-297): 4.35e-10: 64.4: 20.00		EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69
+	Hs
		1349279 ITSN2_HUMAN (196-273): 2.11e-11: 68.4: 30.86		EP15R_HUMAN (12-274): 5.5e-32: 128: 17.60
+	Hs
		61738 A6H8W8_HUMAN (196-273): 2.46e-11: 68.4: 30.86		EP15R_HUMAN (12-274): 5.5e-32: 128: 17.60
+	Hs
		1349275 ITSN2_HUMAN (196-273): 2.11e-11: 68.4: 30.86		ITSN2_HUMAN (3-349): 5.91e-15: 78.1: 12.53
+	Hs
		1078919 ITSN2_HUMAN (196-273): 2.11e-11: 68.4: 30.86		ITSN1_HUMAN (124-241): 2.14e-09: 61.1: 12.30
+	Hs
		1078828 ITSN1_HUMAN (116-297): 4.35e-10: 64.4: 20.00		ITSN1_HUMAN (124-241): 2.14e-09: 61.1: 12.30