HitPredict

Interactor 1: CDN1A (P38936)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)
Gene: CDKN1A

Interactor 2: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	16169070
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 164 Hs			1 347
+	Hs
		758221 CDN1A_HUMAN (1-164): 1.8e-69: 209: 100.00		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		758168 CDN1A_HUMAN (1-164): 1.8e-69: 209: 100.00		HDAC4_HUMAN (1-341): 1.28e-127: 393: 20.53
+	Hs
		758298 CDN1A_HUMAN (1-164): 1.8e-69: 209: 100.00		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		758354 CDN1A_HUMAN (1-164): 1.8e-69: 209: 100.00		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31