HitPredict

Interactor 1: TRAF2 (P39429)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2)
Gene: TRAF2

Interactor 2: M3K7 (Q62073)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: Map3k7

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 22057290, 17384642
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0043507 - positive regulation of JUN kinase activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 501
Mm

1 579
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+ Rn
+ Mm
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+ Dm
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+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024