Interactor 1: TRAF2 (P39429)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2)
Gene: TRAF2

Interactor 2: IRAK1 (Q62406)
Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK)
Gene: IRAK1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 24706909
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0032991 - protein-containing complex
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0043507 - positive regulation of JUN kinase activity
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 501
Mm

1 710
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm

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Last updated: 15 Jul 2024