HitPredict

Interactor 1: ATC3 (P39524)
Phospholipid-transporting ATPase DRS2 (EC 7.6.2.1)
Gene: DRS2

Interactor 2: LEM3 (P42838)
Phospholipid-transporting ATPase accessory subunit LEM3 (Alkylphosphocholine resistance protein LEM3) (Brefeldin-A sensitivity protein 3) (Ro-sensitive 3)
Gene: LEM3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.887

The method score is based on:

Property Details
Experiments 19411703, 37968396, 15090616, 22791719
Identification Methods affinity chromatography technology, protein complementation assay, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC50~PhoLip_ATPase_C, CDC50~PhoLip_ATPase_N
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0045332 - phospholipid translocation
GO:1990531 - phospholipid-translocating ATPase complex
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1355
Sc

1 414
+ Sc
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024